ReviewNature reviews. Urology2026
Observation or treatment of paediatric varicoceles: revisiting the evidence.
Review in Nature reviews. Urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Paediatric varicocele is a common condition affecting ~15% of male adolescents. There is no consensus on an optimal management strategy given that robust data identifying adolescents at risk of long-term testicular dysfunction remain limited. Clinical decision-making is further complicated by heterogeneity in grade, laterality, age at diagnosis and testicular volume disparity. Features favouring observation include low grade, <10% volume asymmetry, hormonal and semen parameters within reference ranges, and low peak retrograde flow on Doppler ultrasonography. Conversely, findings associated with increased risk of future gonadal impairment include high-grade or bilateral varicocele, testicular asymmetry >20%, elevated retrograde flow velocities, and hormonal and semen abnormalities. By synthesizing the available evidence, we propose a risk-stratified model to aid clinicians in selecting appropriate candidates for observation versus early intervention and to guide surveillance through adolescence.
Identifiers
42811152What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.