Evidence map›Paper›PMID 42811139›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Association between the anterior tilt slope and spinal sagittal parameters in asymptomatic adults from Southern China.

Changhe Liao, Haifeng Liang, XinMiao Yu, Tao Ye, Yingqi Gao, Shuang Liang, Dongjuan Liu, Shaojie He, Xiaowen Wang, Yuanfang Lin and 1 more

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Changhe Liao *Department of Orthopaedics, Panyu Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, 511400, Guangzhou, China.
Haifeng Liang *Department of Orthopaedics, Panyu Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, 511400, Guangzhou, China.
XinMiao YuDepartment of Orthopaedics, Panyu Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, 511400, Guangzhou, China.
Tao YeDepartment of Orthopaedics, Panyu Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, 511400, Guangzhou, China.
Yingqi GaoDepartment of Orthopaedics, Panyu Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, 511400, Guangzhou, China.
Shuang LiangDepartment of Orthopaedics, Panyu Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, 511400, Guangzhou, China.
Dongjuan LiuDepartment of Orthopaedics, Panyu Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, 511400, Guangzhou, China.
Shaojie HeDepartment of Orthopaedics, Panyu Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, 511400, Guangzhou, China.
Xiaowen WangDepartment of Orthopaedics, Panyu Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, 511400, Guangzhou, China.
Yuanfang LinDepartment of Tuina and Spinal Orthopaedics in Chinese Medicine, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, 518033, Shenzhen, China. 13602577968@139.com.
Hangzhan MaDepartment of Orthopaedics, Panyu Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, 511400, Guangzhou, China. mahangzhan@126.com.

Funding

Panyu District Science and Technology Plan Project 2020-Z04-004; 2025-Z04-68
6 · The paper itself

Abstract

objectiveTo introduce and validate the Anterior Tilt Slope (ATS) as a novel angular parameter for quantifying cervical forward inclination in asymptomatic young adults, and to examine its associations with cervical and global spinal sagittal parameters.

methodsIn this single-center retrospective study, 341 asymptomatic subjects (18-45 years) who underwent standing full-spine radiographs (AP/Lateral) between May 2023 and May 2025 were analyzed. Cervical parameters (CL, O-C2, C1-7, T1S, cSVA, Borden, ATS), thoracic kyphosis (TK), and spinopelvic parameters (LL, SS, PI, PT, SVA) were measured on PACS by two spine surgeons (twice, averaged). ATS was graded as type I < 5°, II 5-10°, III 10-15°, IV ≥ 15°. Normality was tested with Kolmogorov-Smirnov; group comparisons used t-test/ANOVA with Bonferroni; correlations used Pearson's r (two-tailed α = 0.05). Post hoc power analysis was performed.

resultsThe cohort included 119 males (39%) and 222 females (61%), mean age 25.17 years; overall ATS was 8.17 ± 4.63°. Distribution across ATS grades: I (n = 96), II (n = 134), III (n = 82), IV (n = 29). ATS correlated strongly with cSVA (r = 0.767, P < 0.01) and moderately with T1S (r = 0.482, P < 0.01), and positively with TK (r = 0.252, P < 0.01) and SVA (r = 0.187, P < 0.01); no significant correlations were observed with LL, PI, PT, SS, age, or sex (all P > 0.05). cSVA and T1S increased progressively with higher ATS grades (both P < 0.001). Sex-stratified analyses showed differences in CL, Borden, and C1-7 in certain grades, whereas ATS itself was sex-independent. Statistical power was adequate for main effects.

conclusionsATS provides a robust quantification of cervical forward inclination in asymptomatic individuals, closely linked to cSVA, T1S, and global sagittal alignment, with limited association to spinopelvic parameters-highlighting the pivotal role of the cervicothoracic junction in early sagittal compensation. ATS is a useful complement to cSVA for posture screening, outcome assessment, rehabilitation planning, and potentially surgical decision-making.

Indexed as

Anterior tilt slopeAsymptomatic populationCervical sagittal alignmentcSVAT1 slope

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.