ArticleNature communications2026
Persistent chromatin alterations and gene expression reprogramming follow widespread DNA damage in glioblastoma.
Aram S Modrek, Keerthivasan R Chandradoss, Catherine Do, Ravesanker Ezhilarasan, Theodore Sakellaropoulos, Jerome Karp, Yingwen Ding, Ze-Yan Zhang, Maria L G Quiloan, Melanie Graciani and 4 more
Abstract read
In one paragraphArticle in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
14 authors.
Aram S ModrekDepartment of Radiation Oncology, Keck School of Medicine of USC, Los Angeles, CA, USA.ORCID 0000-0001-7586-9833 Keerthivasan R ChandradossDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Ravesanker EzhilarasanDepartment of Radiation Oncology, NYU Grossman School of Medicine, New York, NY, USA.
Theodore SakellaropoulosDepartment of Pathology, New York University Langone Health, New York, NY, 10016, USA.
Jerome KarpDepartment of Radiation Oncology, NYU Grossman School of Medicine, New York, NY, USA.
Yingwen DingDepartment of Radiation Oncology, NYU Grossman School of Medicine, New York, NY, USA.
Maria L G QuiloanDepartment of Radiation Oncology, Keck School of Medicine of USC, Los Angeles, CA, USA.
Melanie GracianiDepartment of Radiation Oncology, NYU Grossman School of Medicine, New York, NY, USA.
Jennifer E Phillips-CreminsDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.ORCID 0000-0002-4702-0450 Erik P Sulman *Department of Radiation Oncology, NYU Grossman School of Medicine, New York, NY, USA. Erik.Sulman@nyulangone.org.ORCID 0000-0003-4933-9120 Jane A Skok *Department of Pathology, New York University Langone Health, New York, NY, 10016, USA. Jane.Skok@nyulangone.org.ORCID 0000-0002-4145-1516 Funding
The impact of changes in chromatin architecture on cancer phenotypes and tumor progressionP01CA229086 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ADRIANA HEGUY · 2019 to 2026
$17.0MNCI NIH HHS P01 CA229086U.S. Department of Health & Human Services | National Institutes of Health (NIH) P01CA229086
6 · The paper itselfAbstract
DNA damage from routine cellular processes or exogenous insults can have a lasting impact on gene regulation beyond genetic mutations
Indexed as
Brain NeoplasmsChromatinDNA DamageGene Expression Regulation, NeoplasticGlioblastomaCell Line, TumorDNA Breaks, Double-StrandedDNA RepairHumansChromatin
Identifiers
PMID42811032
PMCPMC13623823
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