Evidence map›Paper›PMID 42810982›Full record

ArticlePhysiological reports2026

Enhanced but not superior: Performance outcomes from the inaugural enhanced games.

Rafael A Azevedo, Luis F Coutinho, Monique C Gonçalves, Higor A Oliveira, Guilherme J Gonçalves, Marcus Campos, Hamilton Roschel, Bruno Gualano

Abstract read
In one paragraph

Article in Physiological reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rafael A AzevedoApplied Physiology and Nutrition Research Group, School of Physical Education and Sport, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-0346-7007
Luis F CoutinhoFaculty of Medical Sciences of Minas Gerais (FC MMG), Belo Horizonte, Brazil.
Monique C GonçalvesApplied Physiology and Nutrition Research Group, School of Physical Education and Sport, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil.
Higor A OliveiraApplied Physiology and Nutrition Research Group, School of Physical Education and Sport, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil.
Guilherme J GonçalvesApplied Physiology and Nutrition Research Group, School of Physical Education and Sport, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil.
Marcus CamposSchool of Applied Sciences (FCA), University of Campinas (UNICAMP), Limeira, Brazil.
Hamilton RoschelApplied Physiology and Nutrition Research Group, School of Physical Education and Sport, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil.
Bruno GualanoApplied Physiology and Nutrition Research Group, School of Physical Education and Sport, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0001-7100-8681

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) 001Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) 2023/10778-0
6 · The paper itself

Abstract

The Enhanced Games (TEG) emerged as an athletic event engineered to profit from biotechnological enhancement, such as performance-enhancing drugs (PEDs) utilization, relying on three premises: shattering world records (WR), enabling athletes to surpass their personal bests (PB), and utilizing PEDs to offset age-related physical decline. The effectiveness of TEG's PED protocols in achieving these three premises was evaluated. This is a retrospective analysis from 42 TEG athletes across Track, Swimming, and Weightlifting. TEG's performances were compared to current WR and athletes' PB previous to TEG. The anti-aging PED effects were evaluated by the relationship between the age and performance gaps from PB to TEG competition. Athletes' previous PBs were -5.92% ± 4.68% worse than current WR, which further deteriorated to -8.91% ± 7.52% after TEG, and a single WR was broken. Whereas 19 new PBs were recorded, TEG performances were on average -2.86% ± 7.39% worse than previous PB. Some competitive results were achieved by non-enhanced athletes. Performance decline continued linearly as the time elapsed since the athletes' physical prime (i.e., age at PB). TEG failed to deliver on core promises of widespread WR and broad athletic enhancement, and PED protocol did not attenuate expected age-related performance declines.

Indexed as

Athletic PerformancePerformance-Enhancing SubstancesAthletesDoping in SportsHumansMaleRetrospective StudiesSwimmingPerformance-Enhancing Substancesathletic performancedopingsports performance

Identifiers

PMID42810982
PMCPMC13623661

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.