Evidence map›Paper›PMID 42810755›Full record

ArticleBMJ (Clinical research ed.)2026

Recommendations for evaluating a single surrogate endpoint (REASSurE): consensus based, surrogate evaluation framework with explanation and elaboration.

Wang Pok Lo, Stuart G Baker, Luca Bertolaccini, Sylwia Bujkiewicz, Catey Bunce, Marc Buyse, Oriana Ciani, Robin Christensen, Jane Daniels, Sara Gandini and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ (Clinical research ed.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Wang Pok LoCentre for Population Health Sciences, Usher Institute, School of Population Health Sciences, University of Edinburgh, Edinburgh, UK.
Stuart G BakerIndependent researcher, Columbia, MD, USA.
Luca BertolacciniDepartment of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.
Sylwia BujkiewiczBiostatistics Research Group, Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.
Catey BunceInternational Centre for Eye Health (ICEH), London School of Hygiene and Tropical Medicine, London, UK.
Marc BuyseInternational Drug Development Institute, Louvain-La-Neuve, Belgium.
Oriana CianiCentre for Research on Health and Social Care Management, SDA Bocconi, Milan, Italy.
Robin ChristensenSection for Biostatistics and Evidence-Based Research, the Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.
Jane DanielsNottingham Clinical Trials Unit, University of Nottingham, Nottingham, UK.
Sara GandiniDepartment of Experimental Oncology, IRCCS European Institute of Oncology, Milan, Italy.
Tamer A GheitaRheumatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Peter B GilbertFred Hutchinson Cancer Center, Seattle, WA, USA.
Laura JaegerOffice of New Drugs, Center for Drug Evaluation and Research, United States Food and Drug Administration, Silver Spring, MD, USA.
Dorcas KareithiBiostatistics Research Group, Newcastle University, Newcastle, UK.
Marissa LassereSt George Hospital and School of Population Health, University of New South Wales, Sydney, NSW, Australia.
Nicholas T LongfordSNTL Statistics Research and Consulting, London, UK.
Anthony M ManyaraGlobal Health and Ageing Research Unit, Bristol Medical School, University of Bristol, Bristol, UK.
Koji ObaInterfaculty Initiative in Information Studies, University of Tokyo, Tokyo, Japan.
Emily K RobertsDepartment of Biostatistics, University of Iowa, Iowa City, IA, USA.
Rod S TaylorRobertson Centre for Biostatistics & Primary Care and General Practice, School of Health and Wellbeing, University of Glasgow, Glasgow, UK.
Carlos J Toro-HuamanchumoResearch Unit for Generation and Synthesis Evidence in Health, Saint Ignatius of Loyola University, Lima, Peru.
Steff LewisEdinburgh Clinical Trials Unit, Usher Institute, School of Population Health Sciences, University of Edinburgh, Edinburgh EH16 4UX, UK.
Hannah EnsorEdinburgh Clinical Trials Unit, Usher Institute, School of Population Health Sciences, University of Edinburgh, Edinburgh EH16 4UX, UK.
Christopher J WeirEdinburgh Clinical Trials Unit, Usher Institute, School of Population Health Sciences, University of Edinburgh, Edinburgh EH16 4UX, UK christopher.weir@ed.ac.uk.ORCID https://orcid.org/0000-0002-6494-4903

Funding

Intramural FDA HHS FD999999
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42810755
PMCPMC13714761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.