ArticleChemistry & biodiversity2026
Preparation and Characterization of Ocimum basilicum Extract-Loaded Niosomes and Evaluation of Their Cytotoxic and Pro-Apoptotic Potential in SKOV3 Ovarian Cancer Cells.
Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Niosomes are promising nanocarriers for improving the stability, bioavailability, and delivery of plant-derived bioactive compounds. This study aimed to prepare and physicochemically characterize niosomes loaded with Ocimum basilicum L. extract and evaluate their anticancer and metastasis-related effects in human ovarian cancer SKOV3 cells. The niosomes were characterized using DLS, SEM, FTIR, and in vitro release analysis, showing a mean particle size of 256.2 ± 0.21 nm, PDI of 0.265 ± 0.007, zeta potential of -35.4 ± 0.3 mV, and encapsulation efficiency of 85.2 ± 0.6%. Cytotoxicity was assessed by MTT assay after 24, 48, and 72 h, and the 72 h IC
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