Evidence map›Paper›PMID 42809393›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

PKD2-like proteins target

Poulomi Das, Haixia Zhou, Sneha Sureshkumar, Nathan Chasen, Jin Dai, Alan Brown, Karl Lechtreck

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. PKD2-like proteins targetProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Poulomi DasDepartment of Cellular Biology, University of Georgia, Athens, GA 30602.ORCID 0000-0002-3555-6792
Haixia ZhouDepartment of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.ORCID 0000-0002-9676-6267
Sneha SureshkumarDepartment of Cellular Biology, University of Georgia, Athens, GA 30602.ORCID 0009-0003-3331-3572
Nathan ChasenDepartment of Cellular Biology, University of Georgia, Athens, GA 30602.ORCID 0000-0003-3346-9780
Jin DaiDepartment of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.ORCID 0000-0001-8770-0816
Alan BrownDepartment of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115.ORCID 0000-0002-0021-0476
Karl LechtreckDepartment of Cellular Biology, University of Georgia, Athens, GA 30602.ORCID 0000-0002-6219-6470

Funding

Mechanoregulation of Ciliary MotilityR01GM141109 · NIGMS · HARVARD MEDICAL SCHOOL · PI BROWN, ALAN · 2021 to 2025
$2.1M
Regulation of protein transport in ciliaR35GM152057 · NIGMS · UNIVERSITY OF GEORGIA · PI Karl F. Lechtreck · 2024 to 2026
$1.4M
JEOL 2100PLUS(CR)S10OD034282 · OD · UNIVERSITY OF GEORGIA · PI SALGUERO, TINA · 2023 to 2023
$1.2M
Purchase of a Thermo Fisher Scientific LTQ Orbitrap XL Mass SpectrometerS10RR028859 · NCRR · UNIVERSITY OF GEORGIA · PI AMSTER, I JONATHAN · 2011 to 2011
$832k
HHS | NIH (NIH) R01GM141109HHS | NIH (NIH) R35GM152057NCRR NIH HHS S10 RR028859NIGMS NIH HHS R01 GM141109NIGMS NIH HHS R35 GM152057NIH HHS S10 OD034282
6 · The paper itself

Abstract

Many motile and sensory functions of cilia and flagella depend on the precise localization of transmembrane proteins within the ciliary membrane. Rather than being uniformly distributed, these proteins are often targeted to specific subciliary regions along the length or circumference of cilia. Here, we use genome editing and in vivo imaging to dissect the spatial organization of the channel protein PKD2 in

Indexed as

ChlamydomonasChlamydomonas reinhardtiiCiliaFlagellaciliaflagellaPKD2TRP channels

Identifiers

PMID42809393
PMCPMC13629496

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.