Evidence map›Paper›PMID 42809147›Full record

SynthesisJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2026

A systematic review of the frequency of sleep evaluations, sleep disorders, and treatments among individuals with muscular dystrophy.

Nedra Whitehead, Joyce T Alese, Christine Hill, Mike Enger, Jamie Zimmerman, Amy Moore, Julie Royer, Swamy Venkatash, Shiny Thomas, Barbara Do and 1 more

Erratum issuedAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Nedra WhiteheadRTI International (Retired), 1449 Carter Road, Decatur, GA, 30030, USA.ORCID http://orcid.org/0000-0002-2908-3503
Joyce T AleseDivision of Birth Defects and Infant Disorders National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Christine HillRTI International (Retired), 1449 Carter Road, Decatur, GA, 30030, USA.
Mike EngerRTI International, 3040 East Cornwallis Road, P.O. Box 12194, Research Triangle Park, NC, 27709-219, USA.
Jamie ZimmermanDivision of Birth Defects and Infant Disorders National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Amy MooreRTI International, 307 Waverley Oaks Road, Suite 101, Waltham, MA, 02452-8413, USA. almoore@rti.org.
Julie RoyerSouth Carolina Revenue and Fiscal Affairs Office Data Integration and Analysis Division, Rembert Dennis Bldg. 1000 Assembly St., Suite 240, Columbia, SC, 29201, USA.
Swamy VenkatashDepartment of Neurology, University of South Carolina School of Medicine, 1 Medical Park, Suite 230, Columbia, SC, 29203, USA.
Shiny ThomasNew York Department of Health, Albany, NY, USA.
Barbara DoRTI International, 3040 East Cornwallis Road, P.O. Box 12194, Research Triangle Park, NC, 27709-219, USA.
James F HowardDepartment of Neurology, University of North Carolina, Chapel Hill, NC, 27599-7025, USA.

Funding

JG CDC HHS Centers for Disease Control and Prevention
6 · The paper itself

Abstract

purposeReview literature on the frequency of sleep disorders and receipt of sleep-related healthcare among individuals with muscular dystrophy.

methodsIncluded: Population-Duchenne/Becker (DBMD), congenital (CMD), facioscapulohumeral (FSHD), limb-girdle (LGMD), or myotonic (DM) muscular dystrophy; Outcomes-frequency of sleep evaluations, disorders, or treatments; Language-English; Study type-original research, systematic review. Excluded: Sample <10, duplicate reports. INFORMATION SOURCES: PubMed and EBSCO, last searched March 7, 2023. Risk of bias assessment : Recruitment source or study inclusion selected for or against sleep symptoms or disorders. SYNTHESIS: Range and weighted average (low risk studies only) of outcome.

resultsWe included 95 studies of sleep evaluations (7), disorders (94) or treatments (13) with a total of 7,964 participants. Studies reported on DM-61, DBMD-20, FSHD-9, CMD-1, LGMD-1, and multiple MD-3. One-half of people with DBMD (51%, 2 studies, 85 individuals) and over 60% of people with DM1 (65%, 2 studies, 327 individuals) had a sleep study. Measured by questionnaire, excessive daytime sleepiness frequency among adults with DM was 39% (DM2, 10, 284) to 65% (any DM, 6, 1195), 9% among controls (5, 199), and 6% to 13% among other MDs. Sleep apnea frequency was 11% (LGMD, 1, 18) to 65% (CMD, 1, 20). Assisted ventilation use was 5%-16% (DM).

conclusionsRegular sleep evaluations may improve identification and treatment of sleep disorders and the physical and mental health of individuals with MD. OTHER: Funding-US Centers for Disease Control and Prevention. Not registered.

Indexed as

Muscular DystrophiesSleep Wake DisordersHumansMuscular dystrophiesSleepSleep apnea syndromesSleep Disorders, Intrinsic

Identifiers

PMID42809147
PMCPMC13624246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.