ArticleClinical journal of gastroenterology2026
Rapid intracystic growth of spindle cell-type anaplastic carcinoma derived from intraductal papillary mucinous carcinoma.
Article in Clinical journal of gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Anaplastic carcinoma of the pancreas (ACP) is a rare and aggressive malignancy. We report a case of spindle cell-type ACP arising from intraductal papillary mucinous carcinoma (IPMC) showing rapid intra-cystic growth. A 73 year-old man was incidentally found to have a pancreatic cyst, initially diagnosed as a simple cyst. After 18 months, a solid component appeared within the cyst and rapidly enlarged within one month. Distal pancreatectomy was performed. Histopathology revealed spindle cell-type anaplastic carcinoma arising from invasive IPMC. Despite aggressive histology, curative resection was achieved. The patient remains recurrence-free for 50 months. Rapid changes in pancreatic cysts warrant careful evaluation and timely surgical intervention.
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