Evidence map›Paper›PMID 42809067›Full record

ArticleAnnals of nuclear medicine2026

Assessment of heart-to-contralateral lung ratios in virtual planar images derived from SPECT using

Daichi Ogura, Megumi Kanou, Takuji Toyama, Keiko Koyama, Koichi Okuda, Kenichi Nakajima

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Article in Annals of nuclear medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Daichi OguraDepartment of Radiological Technology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi, 371-0004, Gunma, Japan. t-ogura@cvc.pref.gunma.jp.ORCID http://orcid.org/0009-0009-1900-8145
Megumi KanouDepartment of Radiological Technology, Gunma Prefectural Cardiovascular Center, 3-12 Kameizumi-machi, Maebashi, 371-0004, Gunma, Japan.
Takuji ToyamaDivision of Cardiology, Toyama Cardiovascular Clinic, Maebashi, Gunma, Japan.
Keiko KoyamaDepartment of Radiology, Gunma Prefectural Cardiovascular Center, Maebashi, Gunma, Japan.
Koichi OkudaDepartment of Radiation Science, Graduate School of Health Sciences, Hirosaki University, Hirosaki, Aomori, Japan.
Kenichi NakajimaDepartment of Functional Imaging and Artificial Intelligence, Kanazawa University, Kanazawa, Ishikawa, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveA new AutoPlanar imaging technique can generate virtual planar images from SPECT data. We aimed to determine whether AutoPlanar images can provide accurate heart-to-contralateral lung ratio (H/CL) from

methodsThis retrospective study assessed 41 patients with suspected transthyretin cardiac amyloidosis using

resultsVisual assessment demonstrated good to excellent agreement, with exact agreement ranging from 73.2% to 97.6%. The H/CL ratios derived from AutoPlanar and planar images were highly correlated (r ≥ 0.97). Bland-Altman analysis demonstrated small negative biases (- 0.087 to - 0.027); the 95% limits of agreement were - 0.130 to 0.051 for Flash3D+ with ACRR and - 0.123 to 0.061 for Flash3D+ with ACSCRR. Equivalence testing demonstrated statistical equivalence between planar and AutoPlanar H/CL ratios with ACRR and ACSCRR, whereas equivalence was not demonstrated with RR.

conclusionsThe H/CL ratios derived from AutoPlanar and planar images were comparable. AutoPlanar images were more strongly influenced by correction conditions than by the reconstruction method, with Flash3D+ using ACRR or ACSCRR showing favorable overall results.

Indexed as

99mTc-pyrophosphate scintigraphyAutoPlanar imagingheart-to-contralateral lung ratioSingle-photon emission computed tomographyTransthyretin cardiac amyloidosis

Identifiers

PMID42809067

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.