Evidence map›Paper›PMID 42809066›Full record

ReviewFunctional & integrative genomics2026

Harnessing next-generation molecular technologies for precision control of Tuta absoluta and Helicoverpa armigera in tomato.

Amina Amin Ch, Noman Nazik, Muniba Shahid, Misbah Saleem, Areesha Nadeem, Faisal Saeed, Abdul Qayyum Rao, Iqbal Rashid, Allah Bakhsh

Abstract readReview
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In one paragraph

Review in Functional & integrative genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amina Amin ChSeed Biotech Laboratories, Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Noman NazikSeed Biotech Laboratories, Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Muniba ShahidSeed Biotech Laboratories, Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Misbah SaleemSeed Biotech Laboratories, Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Areesha NadeemInstitute of Molecular Biology and Biotechnology, University of Lahore, Lahore, 54792, Pakistan.
Faisal SaeedSeed Biotech Laboratories, Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Abdul Qayyum RaoSeed Biotech Laboratories, Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan.
Iqbal RashidDepartment of Life Sciences, Western Caspian University, Baku, Azerbaijan.
Allah BakhshSeed Biotech Laboratories, Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, 53700, Pakistan. allahbakhsh@cemb.edu.pk.ORCID https://orcid.org/0000-0003-3561-7863

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tomato (Solanum lycopersicum) is one of the most significant vegetable crops cultivated around the world. Among biotic stresses, production of tomato is severely affected by insect pests mainly by tomato fruit borer (Helicoverpa armigera) and tomato leaf miner (Tuta absoluta). Traditionally to manage the destruction caused by insect pests, farmers mostly used chemical insecticides and by different cultural practices. Use of chemical pesticides is of great concern as it is harmful for the environment and other living beings and with the passage of time, insects develop resistance against pesticides. Latest progress in molecular biology enables scientists to develop next generation pest management approaches that are more precise, environment friendly and sustainable. This review describes nascent molecular approaches to manage tomato pests, like transgenic expression of insecticidal proteins such as of Bacillus thuringiensis (Bt) toxins, RNAi (RNA interference) strategies including HIGS and SIGS, genome editing by CRISPR-Cas, protease inhibitors and male sterility. These strategies not only enhance resistance of crop against pests but also are safe for environment and other organisms. This review also addresses the combination of different molecular approaches and pyramiding of genes involve in delaying resistance. Overall, these advanced molecular approaches providing sustainable resistance against insect pests have been discussed.

Indexed as

Helicoverpa armigeraMothsPest Control, BiologicalSolanum lycopersicumAnimalsCRISPR-Cas SystemsGene EditingPlants, Genetically ModifiedRNA InterferenceGenome editingHelicoverpa armigeraNext generation molecular approachesRNA interferenceTuta absoluta

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.