Evidence map›Paper›PMID 42808951›Full record

ReviewInternational journal of dermatology2026

What Is Pediatric Melanoma? Clinical and Genomic Features and the Role of Next-Generation Sequencing in Tumor Classification.

Michael R Sargen

Abstract readReview
In one paragraph

Review in International journal of dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Michael R SargenDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA.ORCID https://orcid.org/0000-0003-1039-2522

Funding

Division of Cancer Epidemiology and Genetics, National Cancer Institute Intramural FundingIntramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Pediatric melanoma is rare and often poses diagnostic challenges because benign and malignant melanocytic tumors in children can share overlapping clinicopathologic features. Epidemiologic and genomic studies have provided important insights into the etiology of pediatric melanocytic tumors and the genetic alterations associated with malignant transformation. This review summarizes environmental, host, and genetic factors associated with the development of the major pediatric melanoma subtypes, including Spitz melanoma, low-cumulative solar damage (superficial spreading) melanoma, melanoma arising in congenital melanocytic nevi, and melanoma arising in blue nevi. It also highlights key molecular biomarkers associated with pediatric melanoma and presents a diagnostic approach to atypical pediatric melanocytic tumors that illustrates how molecular data can be integrated into tumor classification.

Indexed as

MelanomaNevus, Epithelioid and Spindle CellNevus, PigmentedSkin NeoplasmsBiomarkers, TumorChildHigh-Throughput Nucleotide SequencingHumansMutationNevus, BlueBiomarkers, Tumoradolescent melanomachildhood melanomacongenital melanocytic nevigenomicshereditary melanomanevinext‐generation sequencingpediatric melanomaSpitz melanomaspitzoid melanoma

Identifiers

PMID42808951
PMCPMC13643153

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.