Evidence map›Paper›PMID 42808833›Full record

ArticleVeterinary medicine and science2026

Integrated Biomarker Assessment of Bifenthrin, Chlorpyrifos and Endosulfan Toxicity in Indigenous Carps (Catla catla and Labeo rohita): Oxidative Stress, Genotoxicity and Nuclear Alterations.

Huma Naz, Sajid Abdullah, Tanveer Ahmed, Khalid Abbas, Muhammad Umar Ijaz, Qudrat Ullah, Shabana Naz, Rifat Ullah Khan, Luciana Rossi, Sohail Ahmad and 1 more

Abstract read
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In one paragraph

Article in Veterinary medicine and science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Huma NazDepartment of Zoology, Cholistan Institute of Biological Sciences, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan.
Sajid AbdullahDepartment of Zoology, Wildlife and Fisheries, University of Agriculture Faisalabad, Faisalabad, Pakistan.
Tanveer AhmedDepartment of Life Sciences, Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan, Pakistan.ORCID https://orcid.org/0000-0001-9346-2500
Khalid AbbasDepartment of Zoology, Wildlife and Fisheries, University of Agriculture Faisalabad, Faisalabad, Pakistan.ORCID https://orcid.org/0000-0002-3146-7792
Muhammad Umar IjazDepartment of Zoology, Wildlife and Fisheries, University of Agriculture Faisalabad, Faisalabad, Pakistan.ORCID https://orcid.org/0000-0002-8398-5364
Qudrat UllahDepartment of Theriogenology, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan.ORCID https://orcid.org/0000-0002-5338-5624
Shabana NazDepartment of Zoology, Government College University, Faisalabad, Pakistan.ORCID https://orcid.org/0000-0002-3603-9850
Rifat Ullah KhanPhsyiology Lab, College of Veterinary Sciences, The University of Agriculture Peshawar, Peshawar, Pakistan.ORCID https://orcid.org/0000-0002-0924-0479
Luciana RossiDepartment of Veterinary Medicine and Animal Sciences (DIVAS), University of Milan, Milan, Italy.ORCID https://orcid.org/0000-0003-1178-4683
Sohail AhmadIslamic University, formerly American University of Afghanistan, Kabul, Afghanistan.ORCID https://orcid.org/0000-0001-6845-3418
Rasha AlonaizanDepartment of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.ORCID https://orcid.org/0009-0005-7312-309X

Funding

King Saud University, Riyadh, SaudiArabia ORF-2026-591
6 · The paper itself

Abstract

backgroundThe extensive use of pesticides in agriculture has increased their runoff into aquatic ecosystems, posing serious risks to non-target organisms. Fish are recognized as sensitive bioindicators and are widely used to evaluate the ecological impacts of pesticide contamination.

objectiveThis study investigated the acute toxic effects of bifenthrin + chlorpyrifos (B + C) and bifenthrin + endosulfan (B + E) mixtures on antioxidant enzyme activities, DNA damage and nuclear abnormalities (NAs) in Catla catla and Labeo rohita.

methodsAcute toxicity tests were conducted to determine the 96-h LC

resultsThe 96-h LC

conclusionCombined exposure to bifenthrin-chlorpyrifos and bifenthrin-endosulfan mixtures induces pronounced oxidative stress and genotoxic damage in C. catla and L. rohita, highlighting the usefulness of antioxidant and DNA damage biomarkers for monitoring pesticide contamination in aquatic environments.

Indexed as

CarpsChlorpyrifosDNA DamageEndosulfanInsecticidesOxidative StressPyrethrinsWater Pollutants, ChemicalAnimalsBiomarkersbifenthrinBiomarkersChlorpyrifosEndosulfanInsecticidesPyrethrinsWater Pollutants, Chemicalaquatic ecotoxicologybiomarkersfishpesticide mixturetoxicity assessment

Identifiers

PMID42808833
PMCPMC13621938

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.