Evidence map›Paper›PMID 42808437›Full record

SynthesisJournal of the American Heart Association2026

Blood Pressure Dipping Status in Chronic Kidney Disease and Association With Adverse Outcomes: A Systematic Review and Meta-Analysis.

Sara Abdallah, Ghaidaa El Saddik, Sola Aoun Bahous, Hala Kilani, Siba Kallab, Hicham Cheikh Hassan

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of the American Heart Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Sara AbdallahGilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University Byblos Lebanon.ORCID 0009-0003-4212-030X
Ghaidaa El SaddikGilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University Byblos Lebanon.ORCID 0009-0000-8247-4776
Sola Aoun BahousGilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University Byblos Lebanon.ORCID 0000-0002-7159-7559
Hala KilaniGilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University Byblos Lebanon.
Siba KallabGilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University Byblos Lebanon.ORCID 0000-0001-5043-6329
Hicham Cheikh HassanGilbert & Rose-Marie Chagoury School of Medicine, Lebanese American University Byblos Lebanon.ORCID 0000-0002-9198-6092

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNondipping, <10% nighttime blood pressure reduction, is common in chronic kidney disease (CKD). We conducted a systematic review to determine CKD nondipper prevalence, nondipper risk between patients with and without CKD and adverse events associated with nondippers in CKD.

methodsCKD population studies undergoing an automated blood pressure monitor were searched for on MEDLINE, Embase, and CENTRAL (December 2023), included if they had nondipper information and excluded if they examined only a specific population. Random-effects analysis was conducted to determine prevalence and relative risk (RR) with 95% CI. Risk of bias was assessed with the Joanna Briggs Institute score for prevalence studies and Newcastle-Ottawa Scale for observational studies. A sensitivity analysis excluded studied with a high risk of bias. Heterogeneity was examined using I

resultsWe included 63 articles with 54 515 patients; 33 825 with CKD and 20 690 without CKD. CKD nondipper prevalence was 0.53 (95% CI, 0.52-0.53, SD=13.5%). Compared with patients with CKD, those without CKD had a lower risk of nondipping status (RR, 0.69 [95% CI, 0.63-0.75], SD=14.1%,

conclusionsNondipping is prevalent in CKD, with CKD itself a risk factor. Nondipping was associated with mortality, cardiovascular event, and CKD progression. Almost all included studies were retrospective cohorts, with a high heterogeneity found.

Indexed as

Blood PressureCircadian RhythmHypertensionRenal Insufficiency, ChronicBlood Pressure Monitoring, AmbulatoryHumansPrevalenceRisk AssessmentRisk Factorsambulatory blood pressure monitoringchronic kidney diseasehypertensionmortalityprevalence

Identifiers

PMID42808437
PMCPMC13745101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.