Evidence map›Paper›PMID 42808225›Full record

ArticleBrain pathology (Zurich, Switzerland)2026

Spatial transcriptomic analysis of neurons at the glioma infiltration front: A case study.

Kaishi Satomi, Hirokazu Takami, Hiromi Onizuka, Kuniaki Saito, Takako Yoshioka, Motoo Nagane, Yutaka Suzuki, Koichi Ichimura, Junji Shibahara

Abstract read
In one paragraph

Article in Brain pathology (Zurich, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kaishi SatomiDepartment of Pathology, Kyorin University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0001-7611-5822
Hirokazu TakamiDepartment of Neurosurgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0001-9742-7462
Hiromi OnizukaDepartment of Pathology, Kyorin University School of Medicine, Tokyo, Japan.
Kuniaki SaitoDepartment of Neurosurgery, Kyorin University School of Medicine, Tokyo, Japan.
Takako YoshiokaDepartment of Pathology, National Center for Child Health and Development, Tokyo, Japan.ORCID https://orcid.org/0000-0002-2644-1846
Motoo NaganeDepartment of Neurosurgery, Kyorin University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-0018-1652
Yutaka SuzukiDepartment of Computational Biology and Medical Science, Graduate School of Frontier Science, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0003-4852-1879
Koichi IchimuraDepartment of Pathology, Kyorin University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-3851-2349
Junji ShibaharaDepartment of Pathology, Kyorin University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-8449-7039

Funding

Japan Society for the Promotion of Science London 22K06951School of Medicine, Kyorin University S208090002
6 · The paper itself

Abstract

Spatial transcriptomics reveals localized IGFBP5 expression and TGFβ-related signaling in neurons within glioma-infiltrated tissue.

Indexed as

glioblastomaIDH‐wildtypeIGFBP5spatial transcriptomicsTGFβXenium In Situ

Identifiers

PMID42808225
PMCPMC13621363

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.