ArticleRSC advances2026
DNA detection using metal-enhanced fluorescence.
Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of rapid and sensitive DNA detection methods is critical for advancing diagnostic technologies. This study explores the application of metal-enhanced fluorescence (MEF) to achieve a highly efficient DNA detection system. Gold nanoparticles (AuNPs) were selected due to their ability to amplify fluorescence signals. Ethidium bromide (EB) was employed as the fluorescent dye, given its strong intercalation with DNA and significant fluorescence enhancement upon binding. This system was employed for the detection of double stranded DNA upon formation from binding of single stranded DNA with a complementary probe. To create the detection system, AuNPs were chemically modified with either lipoic acid or aryl diazonium salt to optimize their surface properties. A bench-top fluorimeter was used for detection. The optimized system demonstrated a detection limit as low as 0.4 µg mL
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.