Evidence map›Paper›PMID 42807837›Full record

ArticleRSC advances2026

Hybrid lipid-nanogels: nanolipogels for mRNA delivery.

Ellen Oudkerk-Sodia, Runxin Xu, Renee Chu, Rupali Dabas, Sofia Patri, Christopher Tidd, Luka Blagojevic, Rüdiger Woscholski, Nazila Kamaly

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ellen Oudkerk-SodiaDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub 80 Wood Lane London W12 0BZ UK n.kamaly@imperial.ac.uk r.woscholski@imperial.ac.uk.
Runxin XuDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub 80 Wood Lane London W12 0BZ UK n.kamaly@imperial.ac.uk r.woscholski@imperial.ac.uk.
Renee ChuDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub 80 Wood Lane London W12 0BZ UK n.kamaly@imperial.ac.uk r.woscholski@imperial.ac.uk.
Rupali DabasDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub 80 Wood Lane London W12 0BZ UK n.kamaly@imperial.ac.uk r.woscholski@imperial.ac.uk.
Sofia PatriDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub 80 Wood Lane London W12 0BZ UK n.kamaly@imperial.ac.uk r.woscholski@imperial.ac.uk.
Christopher TiddDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub 80 Wood Lane London W12 0BZ UK n.kamaly@imperial.ac.uk r.woscholski@imperial.ac.uk.
Luka BlagojevicDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub 80 Wood Lane London W12 0BZ UK n.kamaly@imperial.ac.uk r.woscholski@imperial.ac.uk.
Rüdiger WoscholskiDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub 80 Wood Lane London W12 0BZ UK n.kamaly@imperial.ac.uk r.woscholski@imperial.ac.uk.ORCID https://orcid.org/0000-0002-7267-7286
Nazila KamalyDepartment of Chemistry, Imperial College London, Molecular Sciences Research Hub 80 Wood Lane London W12 0BZ UK n.kamaly@imperial.ac.uk r.woscholski@imperial.ac.uk.ORCID https://orcid.org/0000-0002-9716-5121

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoscale drug-delivery systems are central to translating mRNA and other biologic medicines into affordable, scalable products. Existing lipid- and polymer-based carriers are often constrained by costly multi-step syntheses, batch variability and acute immune responses driven by ionisable lipids. Here, we report nanolipogels (NLGs), a hybrid phospholipid-polymer carrier built around a synthetic phospholipid, phosphatidylbutenol, synthesised in a single enzyme-catalysed transphosphatidylation step from 1,2-dioleoyl-

Identifiers

PMID42807837
PMCPMC13617610

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.