Evidence map›Paper›PMID 42807825›Full record

ArticleERJ open research2026

Impaired

Simon O Haas, Nicola Benjamin, Memoona Shaukat, Marc A Schneider, Sarah Richtmann, Natascha Sommer, Karen M Olsson, Marius M Hoeper, Vivienne Theobald, Satenik Harutyunova and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ERJ open research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Simon O HaasCentre for Pulmonary Hypertension, Thoraxklinik Heidelberg at Heidelberg University Hospital, Heidelberg, Germany.ORCID https://orcid.org/0009-0006-3068-3342
Nicola BenjaminCentre for Pulmonary Hypertension, Thoraxklinik Heidelberg at Heidelberg University Hospital, Heidelberg, Germany.
Memoona ShaukatCentre for Pulmonary Hypertension, Thoraxklinik Heidelberg at Heidelberg University Hospital, Heidelberg, Germany.
Marc A SchneiderTranslational Lung Research Centre Heidelberg, Member of the German Centre for Lung Research (DZL), Heidelberg, Germany.ORCID https://orcid.org/0000-0001-8269-3821
Sarah RichtmannTranslational Lung Research Centre Heidelberg, Member of the German Centre for Lung Research (DZL), Heidelberg, Germany.
Natascha SommerMedical Clinic II, Excellence Cluster Cardio-Pulmonary Institute, Member of the DZL, Institute for Lung Health, Justus-Liebig University Giessen, Giessen, Germany.ORCID https://orcid.org/0000-0002-8915-7762
Karen M OlssonDepartment of Pneumology, Hannover Medical School, Biomedical Research in End-stage and Obstructive Lung Disease Hannover, DZL, Hannover, Germany.
Marius M HoeperDepartment of Pneumology, Hannover Medical School, Biomedical Research in End-stage and Obstructive Lung Disease Hannover, DZL, Hannover, Germany.ORCID https://orcid.org/0000-0001-9086-2293
Vivienne TheobaldCentre for Pulmonary Hypertension, Thoraxklinik Heidelberg at Heidelberg University Hospital, Heidelberg, Germany.
Satenik HarutyunovaCentre for Pulmonary Hypertension, Thoraxklinik Heidelberg at Heidelberg University Hospital, Heidelberg, Germany.
Panagiota XanthouliCentre for Pulmonary Hypertension, Thoraxklinik Heidelberg at Heidelberg University Hospital, Heidelberg, Germany.ORCID https://orcid.org/0000-0002-7743-2472
Benjamin EgenlaufCentre for Pulmonary Hypertension, Thoraxklinik Heidelberg at Heidelberg University Hospital, Heidelberg, Germany.
Ekkehard GrünigCentre for Pulmonary Hypertension, Thoraxklinik Heidelberg at Heidelberg University Hospital, Heidelberg, Germany.
Christina A EichstaedtCentre for Pulmonary Hypertension, Thoraxklinik Heidelberg at Heidelberg University Hospital, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In heritable pulmonary arterial hypertension (HPAH) patients, bone morphogenetic protein receptor 2 (BMPR2) signalling and blood mRNA expression are disturbed and reduced. It is unclear whether Methods: In this multicentre, cross-sectional study, a total of 234 subjects were included in seven cohorts: 30 HPAH patients, 38 idiopathic PAH without and 40 idiopathic PAH with comorbidities, 38 systemic sclerosis-associated PAH, 47 CTEPH patients, 9 healthy Results: Conclusion: Our data suggest that

Identifiers

PMID42807825
PMCPMC13617594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.