Evidence map›Paper›PMID 42807425›Full record

ArticleInternational journal of transgender health2026

"I feel under attack": Transgender pre- and adolescents and caregivers opposition to restrictions on gender-affirming medical care in Brazil.

Bruna Caruso Mazzolani, Luana Cordeiro de Oliveira, Igor Longobardi, Fabiana Infante Smaira, Fernanda Sabatini, Fernanda Evangelista Bandeira de Melo, Samuel Bittar, Thifany Helena Torres, Fernanda Baeza Scagliusi, Alexandre Saadeh and 2 more

Abstract read
In one paragraph

Article in International journal of transgender health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bruna Caruso MazzolaniApplied Physiology and Nutrition Research Group, School of Physical Education and Sport and Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-4687-3128
Luana Cordeiro de OliveiraResearch Group in Eating, Corporealities and Culture (GPAC), School of Public Health of the University of Sao Paulo, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0003-0272-9412
Igor LongobardiApplied Physiology and Nutrition Research Group, School of Physical Education and Sport and Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0001-6669-9553
Fabiana Infante SmairaApplied Physiology and Nutrition Research Group, School of Physical Education and Sport and Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0003-4218-4779
Fernanda SabatiniResearch Group in Eating, Corporealities and Culture (GPAC), School of Public Health of the University of Sao Paulo, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-3037-4447
Fernanda Evangelista Bandeira de MeloResearch Group in Eating, Corporealities and Culture (GPAC), School of Public Health of the University of Sao Paulo, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0001-7592-0301
Samuel BittarUniversidade Federal de São Paulo, Campus Baixada Santista, São Paulo, SP, Brazil.ORCID https://orcid.org/0009-0002-5139-9181
Thifany Helena TorresResearch Group in Eating, Corporealities and Culture (GPAC), School of Public Health of the University of Sao Paulo, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-3741-3461
Fernanda Baeza ScagliusiCenter of Lifestyle Medicine, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0001-7590-4563
Alexandre SaadehTransdisciplinary Gender Identity and Sexual Orientation Service (AMTIGOS), Instituto de Psiquiatria do Hospital de Clinicas da Faculdade de Medicina da Universidade de São Paulo HCFMUSP, Universidade de São Paulo, São Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-6591-8838
Hamilton RoschelApplied Physiology and Nutrition Research Group, School of Physical Education and Sport and Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0002-9513-6132
Bruno GualanoApplied Physiology and Nutrition Research Group, School of Physical Education and Sport and Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil.ORCID https://orcid.org/0000-0001-7100-8681

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: In April 2025, Brazil's Federal Council of Medicine (CFM) issued Resolution 2.427/2025 banning puberty blockers, restricting hormone therapy until age 18, and delaying gender-affirming surgeries until age 21. These measures sharply contrast with previous national protocols aligned with international standards of care. We conducted a qualitative study to explore how transgender adolescents and their caregivers perceive these new restrictions. Methods: Nine focus groups were held between May and June 2025 with 5 pre-adolescents and 26 adolescents (11-18 years) and 21 caregivers receiving care at Brazil's largest gender identity outpatient clinic. Discussions were transcribed verbatim, coded, and analyzed using qualitative content analysis. Results: Participants consistently viewed the resolution as unjust, ideologically motivated, and detached from scientific evidence. Adolescents described puberty blockers and hormone therapy as life-saving, emphasizing their positive physical and psychological effects. They rejected detransition as a valid justification for restrictions, framing it as rare and often driven by external pressures. Caregivers echoed these concerns, describing the resolution as harmful, unscientific, and likely to exacerbate inequalities, mental health challenges, and unsafe self-medication practices. Both groups highlighted that gender-affirming care is preceded by long-term, multidisciplinary follow-up under robust clinical protocols, minimizing risks of regret or adverse outcomes. Conclusion: Findings show that restrictive policies are not perceived as neutral regulation but as an assault on the rights, health, and dignity of transgender youth. By amplifying the lived experiences of adolescents and caregivers, this study points out the urgent need for evidence-based, inclusive, and participatory health policies that do not exclude trans voices.

Indexed as

Gender dysphoriagender identityqualitative study sexual orientation

Identifiers

PMID42807425
PMCPMC13618098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.