ReviewFrontiers in immunology2026
Mismatched and underrepresented: bat-virus diversity and phylogeographic bias in experimental infection studies.
Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Despite growing interest in bat-virus interactions, experimental infection studies (EIS) remain taxonomically and geographically restricted, limiting inference about bat immunology and zoonotic risk. We performed a systematic literature search (Jan 1900-Jan 2025) and manually curated peer-reviewed primary studies of viral experimental infections in live bats and bat-derived cell lines (BdCL). From 545 candidate records we retained 127 papers (83 live-bat, 44 BdCL), comprising 315 unique bat-virus trials. We categorized host taxonomy, viral family (ICTV), and biogeographical congruence, to quantify temporal trends, taxonomic coverage, and host-virus pairing patterns. Results show stark underrepresentation: only 45 of ~1,500 bat species (3.2%) and 7 of 21 bat families appear in EIS. Pteropodidae, Vespertilionidae, Phyllostomidae, and Molossidae dominate studies, with
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