ArticleFrontiers in neurology2026
Retained primitive reflexes are independently associated with impaired postural control in adolescents with idiopathic scoliosis.
Article in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Adolescents with idiopathic scoliosis (AIS) exhibit impaired postural control, yet the neurodevelopmental factors underlying this dysfunction remain poorly characterized. Postural control in AIS is heterogeneous, and no clinically accessible neurodevelopmental marker currently exists to identify patients with underlying sensorimotor dysfunction independent of age and radiographic curve severity. Primitive reflexes, brainstem-mediated motor responses that are typically integrated in infancy, have been linked to motor deficits in other neurodevelopmental conditions but have not been investigated in AIS. We tested whether retained primitive reflexes are independently associated with postural control impairment in AIS, after controlling for age and curve severity. Methods: In this cross-sectional study, 48 adolescents with AIS (36 female, 12 male; mean age 11.5 Results: Primitive reflex retention was highly prevalent: 87.2% of participants ( Conclusion: Retained primitive reflexes, particularly the Galant reflex, are independently associated with impaired postural control in AIS beyond age and curve severity. These findings identify primitive reflex retention as a potential neurodevelopmental marker of postural dysfunction within the AIS population.
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