ArticleIJU case reports2026
Paraurethral Endometrioid Carcinoma Arising From Ectopic Endometriosis: A Case Report.
Article in IJU case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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10 authors.
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Abstract
Introduction: Malignant transformation of endometriosis is rare and most commonly involves the ovary; transformation from paraurethral endometriosis is exceedingly rare. Case Presentation: A 73-year-old postmenopausal woman with prior ovarian endometrioma presented with dysuria and voiding difficulty. Positron emission tomography-computed tomography revealed a paraurethral mass at the bladder neck, whereas cystoscopy and urine cytology were normal. Transvaginal biopsy demonstrated adenocarcinoma; however, immunohistochemistry did not identify the primary site. After radical cystectomy with urethrectomy and partial vaginectomy, histopathology showed endometrioid carcinoma arising from paraurethral endometriosis with lymph node metastasis. Comprehensive genomic profiling identified alterations consistent with endometrioid/Müllerian-type carcinoma and compatible with endometriosis-associated carcinogenesis. Despite chemotherapy and immune checkpoint inhibitors, the patient died approximately 16 months after diagnosis. Conclusion: Paraurethral endometrioid carcinoma is exceptionally rare. Accurate diagnosis relies on careful correlation of imaging with histopathology, while comprehensive genomic profiling provides corroborative molecular evidence.
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