Evidence map›Paper›PMID 42807113›Full record

ArticleFrontiers in aging2026

Sex-specific effects of automated feeding on lifespan and reproduction in

Luca Dolfi, Michael Kothmayer, Elmar Erwin Ebner, Renate Löhnert, Oliver Pusch

Abstract read
In one paragraph

Article in Frontiers in aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luca Dolfi *Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
Michael Kothmayer *Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
Elmar Erwin EbnerCenter for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
Renate LöhnertCenter for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
Oliver PuschCenter for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods: Here, we present a novel, cost-effective, and modular automated feeding system for Results: A continuous diet of 24-36 feedings per day increased fish growth in weight but not in length compared to a standard twice-daily regimen. Unexpectedly, while male lifespan remained unaffected by feeding regimen or diet, females subjected to high-frequency automated feeding showed reduced longevity, particularly with high-calorie diets. Additionally, pooled reproductive profiles suggested that reproductive output was associated with dietary fat and protein content as well as feeding frequency. Greater delivered food availability, particularly under high-frequency feeding with energy-rich diets, was associated with increased egg production, reduced embryo survival, and a shortened reproductive period. Discussion: Together, these findings provide important insights for optimizing husbandry and experimental design in

Indexed as

African turquoise killifishautomated feeding systemlifespanNothobranchius furzeripelleted dietsex specificity

Identifiers

PMID42807113
PMCPMC13616631

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.