Evidence map›Paper›PMID 42806695›Full record

ArticleBiotechnology journal2026

In Situ Imaging for Monitoring Biomass Content and Pellet Size in Submerged Filamentous Stirred-Tank Cultivation.

Lukas Hartmann, Tarek Wieland, Linus Witucki, Mike Barth, Dirk Holtmann

Abstract read
In one paragraph

Article in Biotechnology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lukas Hartmann *Karlsruhe Institute of Technology, Karlsruhe, Germany.ORCID https://orcid.org/0000-0003-3357-6244
Tarek Wieland *Karlsruhe Institute of Technology, Karlsruhe, Germany.ORCID https://orcid.org/0009-0008-3575-3658
Linus WituckiKarlsruhe Institute of Technology, Karlsruhe, Germany.ORCID https://orcid.org/0009-0003-4973-9471
Mike BarthKarlsruhe Institute of Technology, Karlsruhe, Germany.ORCID https://orcid.org/0000-0003-2337-063X
Dirk HoltmannKarlsruhe Institute of Technology, Karlsruhe, Germany.ORCID https://orcid.org/0000-0001-5540-3550

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Filamentous microorganisms play a central role in industrial biotechnology, where pellet morphology affects mass transfer, rheology, and process performance. However, time-resolved monitoring of filamentous biomass and pellet size dynamics in stirred-tank reactors remains challenging due to offline sampling limitations. We present a noninvasive in situ imaging approach to observe biomass-related light scattering and projected pellet size. A custom-built camera and ring-light setup with MATLAB-based image acquisition and processing was used to quantify image luminosity as a proxy for biomass content and to determine projected object area (POA) and the number of detected objects per image above a POA threshold of 0.5 mm

Indexed as

Aspergillus oryzaeBiomassBioreactorsImage Processing, Computer-AssistedMalatesmalic acidAspergillus oryzaebioprocess analyticsfungal biomassin situ monitoringpellets

Identifiers

PMID42806695
PMCPMC13620445

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.