Evidence map›Paper›PMID 42806398›Full record

Observational studyBMC research notes2026

Clinical and radiographic evaluation of MTA Flow™ thick as a retrograde filling material in apicoectomy: a preliminary study.

Loan-Chi Thi Bui, Son Hoang Le, Hien Thuc Huu Huynh, Bich-Ly Thi Nguyen

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in BMC research notes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07254143 (Clinical And Radiographic Efficacy Of MTA Flow In Apicoectomy), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07254143 completednot on this map

Clinical And Radiographic Efficacy Of MTA Flow In Apicoectomy

Typeobservational_patient_registrySponsorUniversity of Medicine and Pharmacy at Ho Chi Minh CityRan2021 to 2022Enrolled16ConditionsClinical and Radiographic Success in 6 MonthsArmsMTA flow material
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Loan-Chi Thi BuiDental Department, Military Hospital 175, Ho Chi Minh City, Vietnam.
Son Hoang LeDepartment of Oral Surgery, Faculty of Dentistry, University of Medicine and Pharmacy at Ho Chi Minh City, 652 Nguyen Trai Street, Cho Lon Ward, Ho Chi Minh City, Vietnam. lehoangson@ump.edu.vn.
Hien Thuc Huu HuynhDepartment of General Dentistry, Faculty of Dentistry, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Bich-Ly Thi NguyenDepartment of Oral Surgery, Faculty of Dentistry, University of Medicine and Pharmacy at Ho Chi Minh City, 652 Nguyen Trai Street, Cho Lon Ward, Ho Chi Minh City, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo date, limited evidence exists regarding the clinical efficacy of MTA Flow™ Thick as a retrograde filling material in apicoectomy. This study aimed to investigate the clinical and radiographic outcomes over a 6-month follow-up period following apicoectomy with MTA Flow™ Thick as the retrograde filling material.

resultsA total of 24 teeth from 16 patients were included in this prospective study. All apicoectomies were performed by a single oral surgeon following a standardised surgical protocol. Clinical and radiographic outcomes were assessed at 3 and 6 months. All clinical symptoms-pain, swelling, and fistulas-showed a statistically significant reduction at both follow-up intervals (p < 0.001 for all). Periapical lesion size decreased at both time points (p < 0.001). Radiographic healing was observed in ≥ 85.5% of cases and demonstrated progressive improvement between the two follow-ups. The overall success rate increased significantly from 83.3% at 3 months to 91.7% at 6 months. Trial registration This study was registered at ClinicalTrials.gov (Identifier: NCT07254143, date 28 November 2025). This is a retrospectively registered trial.

Indexed as

Aluminum CompoundsApicoectomyCalcium CompoundsOxidesRoot Canal Filling MaterialsSilicatesAdultDrug CombinationsFemaleHumansMaleMiddle AgedProspective StudiesTreatment OutcomeAluminum CompoundsCalcium CompoundsDrug Combinationsmineral trioxide aggregateOxidesRoot Canal Filling MaterialsSilicatesApicoectomyMineral trioxide aggregateMTA Flow™Periapical healingRetrograde filling

Identifiers

PMID42806398
PMCPMC13621695

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.