Evidence map›Paper›PMID 42806307›Full record

Observational studyBMC infectious diseases2026

Wound infections due to factory gunpowder and pyrotechnic explosions in patients with burn injury: risk factors and antimicrobial resistance.

Jinfu Li, Yueying Fan, Xiangong Jiao, Ming Zou, Zhangjia Jiang, Cheng Li, Shiqiang Jiang, Chiyu Jia

Abstract readObservational Study
In one paragraph

Observational study in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jinfu Li *Center of Burn & Plastic and Wound Healing Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.
Yueying Fan *Center of Burn & Plastic and Wound Healing Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.
Xiangong Jiao *Department of Burn and Reconstructive Surgery, Liuyang People's Hospital, 452 Dao wu West Road, Liuyang, Hunan, 410300, China.
Ming ZouDepartment of Burn and Reconstructive Surgery, Liuyang People's Hospital, 452 Dao wu West Road, Liuyang, Hunan, 410300, China.
Zhangjia JiangDepartment of Burn and Reconstructive Surgery, Liuyang People's Hospital, 452 Dao wu West Road, Liuyang, Hunan, 410300, China.
Cheng LiCenter of Burn & Plastic and Wound Healing Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.
Shiqiang JiangCenter of Burn & Plastic and Wound Healing Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.
Chiyu JiaCenter of Burn & Plastic and Wound Healing Surgery, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China. jiachiyu309@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA substantial obstacle in the treatment of burn patients is the management of burn wound infection (BWI). The objective of this investigation was to assess the antimicrobial susceptibility test results and distribution characteristics of microorganisms isolated from the burn wounds of patients affected by the factory gunpowder and pyrotechnic explosions.

methodsThis tertiary burn center conducted a 5-year retrospective observational study of the clinical and laboratory characteristics of pathogenic microorganisms through drug susceptibility tests, species distribution, and timing of wound infections. Two groups of patients were compared: patients with burn wound infection (BWI) versus patients without burn wound infection (Non-BWI).

resultsThe study enrolled 313 individuals (median age: 47 years), of whom 286 (91.37%) were male. One hundred twenty‑four (39.6%) developed BWI. Multiple regression analysis showed that inhalation injury, length of stay (LOS), and percentage total body surface area (%TBSA) were independent risk factors for developing BWI. The most frequently isolated bacteria were Acinetobacter baumannii (31.6%) and Klebsiella pneumoniae (10.9%). The median time from admission to first pathogen isolation was 12 days (IQR: 4-25 days) for Gram‑negative bacteria, 20 days (IQR: 10-30 days) for Gram‑positive bacteria, and 35 days (IQR: 18.5-59.5 days) for fungi.

conclusionBWI occurred in 39.6% of gunpowder-related burn patients. Independent risk factors were inhalation injury (OR 4.86), larger %TBSA (OR 1.08), and prolonged LOS (OR 1.09). Gram-negative pathogens predominated (74.4%), with A. baumannii (31.6%) showing near-complete resistance. Gram-negative infections emerged earlier (median 12 days) than Gram-positive (20 days) or fungi (35 days). Based on these findings, our burn unit now initiates early surveillance cultures at day 7 post-admission for high-risk patients, prioritizes empiric Gram-negative coverage (specifically anti-Acinetobacter therapy) in the first two weeks, and has implemented enhanced infection control protocols targeting A. baumannii transmission.

Indexed as

BurnsDrug Resistance, BacterialExplosionsWound InfectionAcinetobacter baumanniiAdultAgedAnti-Bacterial AgentsBacteriaFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedRetrospective StudiesRisk FactorsAnti-Bacterial AgentsBurn woundEpidemiologyGunpowderInfectionPathogenResistanceRisk factors

Identifiers

PMID42806307
PMCPMC13621655

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.