Evidence map›Paper›PMID 42806265›Full record

ArticleNeurocritical care2026

Early Arterial Oxygen Tension Thresholds for Mechanically Ventilated Patients with Non-traumatic Acute Brain Injury: A Bayesian Analysis of Three Large Neurocritical Care Datasets.

Lavienraj Premraj, Christopher Camarda, Nekane Romero-Garcia, Benjamin Seymour, Ashwin Subramaniam, Rafael Badenes, Denise Battaglini, Shahzad Shaefi, David Pilcher, Sung-Min Cho and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Neurocritical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lavienraj Premraj *Department of Acute and Critical Care, School of Public Health and Preventive Medicine, Faculty of Medicine Nursing and Health Sciences, Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), Monash University, Melbourne, Australia. Lavienraj.premraj@monash.edu.ORCID http://orcid.org/0000-0003-3682-3722
Christopher Camarda *Monash Health, Melbourne, VIC, Australia.
Nekane Romero-GarciaDepartment of Anaesthesiology and Critical Care, Hospital Clínico Universitario de Valencia, University of Valencia, Valencia, Spain.
Benjamin SeymourIntensive Care Unit, Gold Coast University Hospital, Southport, QLD, Australia.
Ashwin SubramaniamDepartment of Acute and Critical Care, School of Public Health and Preventive Medicine, Faculty of Medicine Nursing and Health Sciences, Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), Monash University, Melbourne, Australia.
Rafael BadenesDepartment of Anaesthesiology and Critical Care, Hospital Clínico Universitario de Valencia, University of Valencia, Valencia, Spain.
Denise BattagliniIRCCS Azienda Ospedaliera Metropolitana, Genova, Italy.
Shahzad ShaefiDepartment of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA.
David PilcherDepartment of Acute and Critical Care, School of Public Health and Preventive Medicine, Faculty of Medicine Nursing and Health Sciences, Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), Monash University, Melbourne, Australia.
Sung-Min ChoDivision of Neurosciences Critical Care, Departments of Neurology, Surgery, Anaesthesiology and Critical Care Medicine, Johns Hopkins Hospital, Baltimore, MD, USA.
Nicole M WhiteAustralian Centre for Health Services Innovation and Centre for Healthcare Transformation, Queensland University of Technology, Brisbane, Australia.
Aidan BurrellDepartment of Acute and Critical Care, School of Public Health and Preventive Medicine, Faculty of Medicine Nursing and Health Sciences, Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), Monash University, Melbourne, Australia.
Raphaël CinottiDivision Anesthésie-Réanimation, Hôtel-Dieu, Université de Nantes, Nantes, France.
Chiara RobbaIRCCS Azienda Ospedaliera Metropolitana, Genova, Italy.
Andrew Alexander UdyDepartment of Acute and Critical Care, School of Public Health and Preventive Medicine, Faculty of Medicine Nursing and Health Sciences, Australian and New Zealand Intensive Care Research Centre (ANZIC-RC), Monash University, Melbourne, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOptimal arterial oxygen tension (PaO

methodsThis retrospective multicenter cohort study utilized the Australian and New Zealand Intensive Care Society Adult Patient Dataset (ANZICS-APD; N = 11,264). Bayesian logistic regression was performed with day 1 PaO

resultsOf the 11,264 patients in the ANZICS-APD suitable for analysis, 4846 had ICH, 4319 had aneurysmal SAH, and 2099 had AIS. Across all ABI types, day 1 PaO

conclusionsIn mechanically ventilated patients with nontraumatic ABI, we defined generalizable early PaO

Indexed as

Intracranial haemorrhagesStrokeSubarachnoid haemorrhage

Identifiers

PMID42806265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.