Evidence map›Paper›PMID 42806170›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026

Impact of orthogeriatric care: prescription patterns in hospitalized older adults.

Sofia Mendes-Piteira, Filipa Fialho Reis, Hugo Alexandre Ferreira, Catarina Oliveira, Francisco Serra Alves, Ana Margarida Silva, Alexandra Resende, Mariana Alves

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Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

8 authors.

Sofia Mendes-PiteiraFaculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal. anasofiapiteira@edu.ulisboa.pt.ORCID http://orcid.org/0009-0006-4780-7110
Filipa Fialho ReisUnidade Local de Saúde Santa Maria, Lisboa, Portugal.ORCID http://orcid.org/0000-0002-9676-9417
Hugo Alexandre FerreiraFaculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.ORCID http://orcid.org/0000-0002-4323-3942
Catarina OliveiraUnidade Local de Saúde Santa Maria, Lisboa, Portugal.ORCID http://orcid.org/0009-0000-0551-3700
Francisco Serra AlvesUnidade Local de Saúde Santa Maria, Lisboa, Portugal.
Ana Margarida SilvaUnidade Local de Saúde Santa Maria, Lisboa, Portugal.
Alexandra ResendeUnidade Local de Saúde Santa Maria, Lisboa, Portugal.ORCID http://orcid.org/0000-0001-5890-860X
Mariana AlvesFaculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.ORCID http://orcid.org/0000-0002-1369-8423

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orthogeriatric co-management aims to optimize care for high-risk hip fracture patients. Implementation significantly increased secondary prevention (osteoporosis/anemia) and reduced intramuscular haloperidol. With a 63% relative reduction in mortality (8.6% to 3.2%), this model proves essential for enhancing safety and survival in complex older populations. PURPOSE: Proximal femoral fractures (PFF) impose a substantial burden on older adults and healthcare systems. Orthogeriatric co-management aims to optimize care for this high-risk population, yet its influence on in-hospital prescribing is poorly characterized. This study examines how implementing an orthogeriatric unit affects medication patterns in hospitalized older adults with PFF.

methodsA 23-month retrospective, observational study included consecutively admitted PFF patients aged ≥65 years. Clinical and pharmacological data (demographics, chronic medications, length of stay, surgical timing) were extracted from electronic and pharmacy records. In-hospital prescribing was assessed across key domains: analgesia, anaemia, delirium, antimicrobial stewardship, bowel regulation, and osteoporosis. Pre- and post-implementation cohorts were compared using descriptive statistics, chi-squared, and t tests (p < 0.05).

resultsA total of 872 patients were included in the study. Implementation of the orthogeriatric unit was associated with significant increases in the prescription of laxatives (lactulose: 8.1% vs 74.5% p < 0.001; oral bisacodyl: 2.7% vs 48.9% p < 0.001), haematopoietic therapies (folic acid: 6.8% vs 22.0% p < 0.001; ferric carboxymaltose: 1.4% vs 20.6% p < 0.001), and secondary fracture prevention treatments (calcium: 2.7% vs 51.5% p < 0.001; vitamin D: 2.5% vs 56.7% p < 0.001; zoledronic acid: 1.4% vs 12.7% p < 0.001). Intramuscular haloperidol use significantly decreased (21.7% vs 10.9% p < 0.001). Oral paracetamol use increased, while opioid prescribing remained stable. Unadjusted intra-hospital mortality declined significantly (7.7% vs 2.9%, p = 0.005).

conclusionThe orthogeriatric approach successfully streamlined both management across key therapeutic domains and patient survival. This study quantifies the positive impact of co-management, supporting evidence for the implementation of safer, proactive therapeutic protocols in hip fracture care.

Indexed as

OrthogeriatricsPharmacological prescribingPolypharmacyProximal femoral fracture

Identifiers

PMID42806170

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.