Evidence map›Paper›PMID 42806152›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2026

A comparison of the efficacy of cognitive-behavioral stress management and acceptance and commitment therapy on the quality of life and fatigue of caregivers of patients with cancer: a randomized controlled trial.

Fateme Al-Sadat Hosseini, Azadeh Choobforoushzadeh, Seyed Mohammad Reza Mortazavizadeh, Yasser Rezapour Mirsaleh

Registry-linked trialAbstract readRandomized Controlled TrialComparative StudyEquivalence Trial
PubMed Publisher
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07329868 (Comparing the Effectiveness of Acceptance and Commitment Therapy and Cognitive Behavioral Stress Management on Fear of Recurrence, Quality of Life, Psychological Distress, and Fatigue of Caregivers of Cancer Patients), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07329868 nacompletednot on this map

Comparing the Effectiveness of Acceptance and Commitment Therapy and Cognitive Behavioral Stress Management on Fear of Recurrence, Quality of Life, Psychological Distress, and Fatigue of Caregivers of Cancer Patients

TypeinterventionalSponsorArdakan UniversityRan2024 to 2024Enrolled66ConditionsCaregiver BurdenArmsCognitive Behavioral Stress Management (CBSM), Acceptance and Commitment Therapy (ACT)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fateme Al-Sadat HosseiniDepartment of Psychology, Faculty of Humanities & Social Sciences, Ardakan University, Ardakan, Iran.
Azadeh ChoobforoushzadehDepartment of Psychology, Faculty of Humanities & Social Sciences, Ardakan University, Ardakan, Iran. azadechoobforoush@ardakan.ac.ir.ORCID http://orcid.org/0000-0002-5778-1165
Seyed Mohammad Reza MortazavizadehDepartment of Hematology and Oncology, Islamic Azad University, Yazd Branch, Yazd, Iran.
Yasser Rezapour MirsalehDepartment of Counseling, Faculty of Humanities and Social Sciences, Ardakan University, Ardakan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study sought to compare the effectiveness of cognitive behavioral stress management (CBSM) and acceptance and commitment therapy (ACT) on the quality of life and fatigue of caregivers of cancer patients.

methodThis single-site, parallel-group, three-arm, superiority randomized controlled trial with a 1:1:1 allocation ratio includes 66 caregivers of cancer patients who were randomly assigned to either the CBSM, ACT, or control group. The CBSM and ACT interventions each consisted of eight in-person sessions, conducted twice a week for 90 min each. Participants in all three groups completed the Caregiver Quality of Life Index-Cancer and the Multidimensional Fatigue Inventory in all pre, post, and follow-up phases.

resultsA significant difference was observed in the quality of life and caregiver fatigue among the three groups in both the posttest and follow-up phases (p < 0.05), which were maintained 2 months after the intervention, apart from quality of life in the CBSM group. However, there was no statistically significant difference in the variables between the two interventions (p > 0.05).

conclusionThe effectiveness of both ACT and CBSM in enhancing caregivers' quality of life and alleviating fatigue offers a promising perspective for the development and implementation of supportive and therapeutic programs aimed at enhancing the mental health of caregivers of cancer patients.

trial registrationwww. CLINICALTRIALS: gov , NCT07329868 (December 29, 2025, retrospectively registered).

Indexed as

Acceptance and Commitment TherapyCaregiversCognitive Behavioral TherapyFatigueNeoplasmsQuality of LifeStress, PsychologicalAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedAcceptance and commitment therapyCancerCaregiversCognitive behavioral stress managementFatigueQuality of life

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.