Evidence map›Paper›PMID 42806081›Full record

ArticleNature nanotechnology2026

Mechanical stress remodelling drives epithelial-mesenchymal transition in the tumour microenvironment.

Minji An, Ri Yu, Annie Lin, Jinho Jang, Jiyeon Ohk, Jaemog Jung, Young-Joo Kim, Hosung Jung, Minsuk Kwak, Young-Wook Jun and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature nanotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Minji AnCenter for NanoMedicine, Institute for Basic Science (IBS), Seoul, Republic of Korea.
Ri YuCenter for NanoMedicine, Institute for Basic Science (IBS), Seoul, Republic of Korea.ORCID http://orcid.org/0009-0007-7188-2038
Annie LinDepartment of Otolaryngology, University of California, San Francisco, San Francisco, CA, USA.
Jinho JangCenter for NanoMedicine, Institute for Basic Science (IBS), Seoul, Republic of Korea.
Jiyeon OhkDepartment of Anatomy, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jaemog JungCenter for NanoMedicine, Institute for Basic Science (IBS), Seoul, Republic of Korea.ORCID http://orcid.org/0009-0002-3138-9103
Young-Joo KimCenter for NanoMedicine, Institute for Basic Science (IBS), Seoul, Republic of Korea.
Hosung JungDepartment of Anatomy, Graduate School of Medical Science, Brain Korea 21 Project, Yonsei University College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-5059-8050
Minsuk KwakCenter for NanoMedicine, Institute for Basic Science (IBS), Seoul, Republic of Korea.ORCID http://orcid.org/0000-0002-8095-532X
Young-Wook JunDepartment of Otolaryngology, University of California, San Francisco, San Francisco, CA, USA. young-wook.jun@ucsf.edu.ORCID http://orcid.org/0000-0003-3182-5366
Jinwoo CheonCenter for NanoMedicine, Institute for Basic Science (IBS), Seoul, Republic of Korea. jcheon@yonsei.ac.kr.ORCID http://orcid.org/0000-0001-8948-5929

Funding

Spatiotemporal interrogation of molecular mechanobiololgy at the cell-cell interface with nanotechnology toolsR35GM134948 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Young-wook Jun · 2020 to 2026
$3.6M
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (NIGMS) R35GM134948
6 · The paper itself

Abstract

The dynamic mechanical response of tissues underlies their physiological function; yet a direct, quantitative measurement of tissue stress in vivo has remained a major challenge. Here we introduce the mechanoMR microparticle sensor, a platform that transduces local tissue mechanical stress into quantitative magnetic resonance read-outs with single-particle resolution. The sensor comprises alginate hydrogel microparticles (~70 μm) homogeneously embedded with Zn

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.