ArticleEuropean journal of applied physiology2026
Exercise modality influences oxygen pulse flattening during incremental cardiopulmonary exercise testing in healthy adults.
Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeTo compare oxygen pulse (O₂P) responses during cardiopulmonary exercise testing (CPET) in healthy adults using two ergometers, Treadmill and Cycle ergometer, and to determine the prevalence of O₂P flattening and the modality-specific characteristics of O₂P curve dynamics.
methodsThirty-four healthy adults (29.4 ± 6.9 years; 35% female) completed two maximal CPETs on both Cycle and Treadmill, in a random order within three weeks. O₂P flattening, defined as the absence of a further increase in O₂P despite increasing workload, was assessed visually and confirmed quantitatively.
resultsTwelve participants (35%) demonstrated O₂P flattening or decline, nine (27%) exclusively during Treadmill testing. A significant group × modality interaction was observed for peak O₂P (p < 0.05), with lower values in participants with flattening than in those showing a continuous rise. (Cycle: 9.9 ± 3.2 vs. 13.6 ± 2.7 ml/min/beat; Treadmill: 11.8 ± 3.7 vs. 16.6 ± 3.7 ml/min/beat). In addition, an O
conclusionO₂P flattening was more frequently observed during treadmill exercise, indicating that O₂P trajectories are exercise modality dependent. In individuals with low peak O₂P during cycle ergometry, additional assessment using treadmill CPET may offer complementary information.
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