Evidence map›Paper›PMID 42806067›Full record

ReviewNature reviews. Microbiology2026

Bifidobacteria: biogeography, host adaptation and ecological functions.

Chiara Tarracchini, Christian Milani, Charlotte N L Jones, Francesca Turroni, Grace Burgess, Jennifer Mahony, Lindsay J Hall, Marco Ventura, Douwe van Sinderen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chiara Tarracchini *Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy.ORCID http://orcid.org/0000-0003-2578-0050
Christian Milani *Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy.
Charlotte N L JonesDepartment of Microbes, Infection and Microbiomes, School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Francesca TurroniLaboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy.
Grace BurgessDepartment of Microbes, Infection and Microbiomes, School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Jennifer MahonyFood, Microbiome and Health, Quadram Institute Bioscience, Norwich Research Park, Norwich, UK.ORCID http://orcid.org/0000-0001-5846-6303
Lindsay J HallDepartment of Microbes, Infection and Microbiomes, School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Marco VenturaLaboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy. marco.ventura@unipr.it.
Douwe van SinderenAPC Microbiome Institute and School of Microbiology, Bioscience Institute, National University of Ireland, Cork, Ireland. d.vansinderen@ucc.ie.ORCID http://orcid.org/0000-0003-1823-7957

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bifidobacteria are widely recognized important symbionts of the human gut microbiome, shaping host physiology from birth to adulthood to old age. Their evolutionary success is derived from metabolic versatility, ecological adaptation and intimate host interactions. Equipped with an expansive glycan-degrading repertoire, stress-response systems and specialized cell surface structures, bifidobacteria establish stable gut colonization and influence host immune, metabolic and neuroendocrine functions. Genomics and functional studies have revealed how human-associated members of this genus shape trophic networks, tolerance and resilience within the gut ecosystem. Integration of ecological, metabolic and immunological perspectives now positions the genus Bifidobacterium as an excellent model to support human gut health and its potential use as gut microbiota-based therapeutics.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.