Evidence map›Paper›PMID 42805189›Full record

Trial reportHormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme2026

Feasibility of Fast Turnaround Genetic Screening for Type 1 Diabetes Risk in Newborns - Recruiting Infants for the Global Platform for the Prevention of Autoimmune Diabetes Primary Prevention Study Supplementation with B ifidobacterium infantis for Mitigation of Type 1 Diabetes Autoimmunity.

Annika Fehn, Ezio Bonifacio, Elisa Bonnin, Kristina Casteels, Melanie Gündert, Martin Heigermoser, Ida Jönsson, Olga Kordonouri, Anja Loff, Markus Lundgren and 10 more

Abstract readMulticenter StudyClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Annika FehnHelmholtz Center Munich German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.
Ezio BonifacioHelmholtz Center Munich German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.
Elisa BonninHelmholtz Center Munich German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.
Kristina CasteelsKU Leuven University Hospitals Leuven Gasthuisberg Campus, Department of Pediatrics, Flanders, Belgium, Leuven.
Melanie GündertHelmholtz Center Munich German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.
Martin HeigermoserHelmholtz Center Munich German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.
Ida JönssonLund University, Unit for Pediatric Endocrinology, Department of Clinical Sciences Malmö, Skåne County, Sweden, Lund.
Olga KordonouriAuf der Bult Children's Hospital, Hannoversche Kinderheilanstalt, NDS, Germany, Hanover.
Anja LoffTechnische Universität Dresden, Center for Regenerative Therapies, SN, Germany, Dresden.
Markus LundgrenLund University, Unit for Pediatric Endocrinology, Department of Clinical Sciences Malmö, Skåne County, Sweden, Lund.
Mariusz OłtarzewskiInstytut Matki i Dziecka, Department of Screening and Metabolic Diagnostics, Masovian Voivodeship, Poland, Warsaw.
Catherine OwenGreat North Children's Hospital, General Paediatrics, England, United Kingdom of Great Britain and Northern Ireland, Newcastle upon Tyne.
Stephen RobsonGreat North Children's Hospital, General Paediatrics, England, United Kingdom of Great Britain and Northern Ireland, Newcastle upon Tyne.
Frank RoloffAuf der Bult Children's Hospital, Hannoversche Kinderheilanstalt, NDS, Germany, Hanover.
Agnieszka SzypowskaUniversity Clinical Center of the Medical University of Warsaw, Department of Paediatric Diabetology and Paediatrics, Masovian Voivodeship, Poland, Warsaw.
Anne RochtusKU Leuven University Hospitals Leuven Gasthuisberg Campus, Department of Pediatrics, Flanders, Belgium, Leuven.
Andreas WeissHelmholtz Center Munich German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.
Christiane WinklerHelmholtz Center Munich German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.
Anette-Gabriele ZieglerHelmholtz Center Munich German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.
Florian HauptHelmholtz Center Munich German Research Center for Environmental Health, Institute of Diabetes Research, Germany, Neuherberg.

Funding

Leona M. and Harry B. Helmsley Charitable Trust #2003-04286 GPPAD coordinating center continuation, #2007-04031 GPPAD-04 study: Supplementation with B,#2018PG-T1D022 GPPAD-02 study and GPPAD coordinati, #2110-04841 Continuation of the GPPAD-02-Study: Ide
6 · The paper itself

Abstract

Abstract: Screening using polygenic risk scores can identify infants at increased risk for islet autoimmunity and type 1 diabetes. The Supplementation with

Indexed as

AutoimmunityDiabetes Mellitus, Type 1Genetic TestingNeonatal ScreeningPrimary PreventionFeasibility StudiesFemaleGenetic Predisposition to DiseaseHumansInfantInfant, NewbornMaleRisk Factors

Identifiers

PMID42805189
PMCPMC13686779

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.