ArticleProceedings of the National Academy of Sciences of the United States of America2026
Climate-amplified wildland-urban interface disasters create persistent internal metal mixtures associated with pulmonary impairment.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Climate-amplified wildland-urban interface disasters create persistent internal metal mixtures associated with pulmonary impairment.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
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Authors and funding
11 authors.
Funding
Abstract
Wildland-urban interface (WUI) wildfires are increasingly important climate-related exposure events because they burn built infrastructure and can mobilize legacy contaminants in addition to generating smoke. Although the acute respiratory effects of wildfire smoke are well described, persistent internal metal mixtures and their association with pulmonary function after WUI disasters remain poorly characterized. Using the August 2023 Maui wildfires as a sentinel model, we evaluated 1,400 adults enrolled 6 to 18 mo after the disaster in a community-engaged cohort. We measured 24 urinary metals and assessed pulmonary function by standardized spirometry at the same visit, enabling paired exposure-response analyses. Compared with US reference levels, participants exhibited elevated internal metal burdens, including antimony (40-fold), manganese (3.8-fold), barium (2.3-fold), and arsenic (2.2-fold), with the highest concentrations clustering in the most affected regions. Across three complementary mixture-modeling approaches, higher cumulative metal burden was consistently associated with greater odds of abnormal spirometry. In weighted quantile sum models, each 1-quantile increase in the positive mixture index, driven primarily by arsenic, cadmium, and copper, was associated with higher odds of FVC, FEV
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