Evidence map›Paper›PMID 42804292›Full record

ArticleEuropean journal of psychotraumatology2026

Project Harmony 2.0: protocol for an updated and expanded individual patient data meta-analysis and virtual clinical trial of treatments for comorbid PTSD and substance use disorders.

Denise A Hien, Shannon M Blakey, Sonya B Norman, Therese K Killeen, Lissette M Saavedra, Sudie E Back, Teresa Lopez-Castro, Tracy L Simpson, Margaret Swarbrick, Ismene Petrakis and 5 more

Abstract read
In one paragraph

Article in European journal of psychotraumatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Denise A HienGraduate School of Applied and Professional Psychology, Rutgers Center of Alcohol & Substance Use Studies, Piscataway, NJ, USA.ORCID 0000-0002-6954-2882
Shannon M BlakeyRTI International, Durham, NC, USA.ORCID 0000-0002-9291-3688
Sonya B NormanNational Center for PTSD, Executive Division, White River Junction, VT, USA.ORCID 0000-0002-4751-1882
Therese K KilleenMedical University of South Carolina, Charleston, SC, USA.ORCID 0000-0002-5142-0908
Lissette M SaavedraRTI International, Durham, NC, USA.ORCID 0000-0001-8880-0624
Sudie E BackMedical University of South Carolina, Charleston, SC, USA.ORCID 0000-0002-7683-8737
Teresa Lopez-CastroThe City College of New York, New York, NY, USA.
Tracy L SimpsonCenter of Excellence in Substance Addiction Treatment and Education, Seattle, WA, USA.
Margaret SwarbrickGraduate School of Applied and Professional Psychology, Rutgers Center of Alcohol & Substance Use Studies, Piscataway, NJ, USA.
Ismene PetrakisYale School of Medicine, New Haven, CT, USA.
Katherine MillsThe Matilda Centre for Research in Mental Health and Substance Use, University of Sydney, Camperdown, NSW, Australia.ORCID 0000-0002-9714-1832
Lesia M RuglassThe City College of New York, New York, NY, USA.
Debra KaysenStanford University School of Medicine, Stanford, CA, USA.ORCID 0000-0001-7961-2787
Angelo M DiBelloGraduate School of Applied and Professional Psychology, Rutgers Center of Alcohol & Substance Use Studies, Piscataway, NJ, USA.ORCID 0000-0002-3913-0086
Antonio A Morgan-LópezRTI International, Durham, NC, USA.ORCID 0000-0003-4706-9964

Funding

Meta-analysis of Individual Patient Data for PTSD/AODsR01AA025853 · NIAAA · RESEARCH TRIANGLE INSTITUTE · PI HIEN, DENISE AIMEE, MORGAN-LOPEZ, ANTONIO A · 2018 to 2021
$1.7M
Advancing patient-centered research using meta-analysis of individual patient data to identify clinically significant trajectories of PTSD/SUD and recovery outcomesR01DA061338 · NIDA · RUTGERS, THE STATE UNIV OF N.J. · PI DENISE AIMEE HIEN, ANTONIO A MORGAN-LOPEZ · 2025 to 2026
$1.7M
NIAAA NIH HHS R01 AA025853NIDA NIH HHS R01 DA061338
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Stress Disorders, Post-TraumaticSubstance-Related DisordersComorbidityHumansMeta-Analysis as TopicRandomized Controlled Trials as TopicResearch Designanéalisis integrador de datosarmonización de datoscambio clínicamente significativoclinically significant changedata harmonizationFAIR data principlesintegrative data analysismeta-analysis of individual patient datametanálisis de datos individuales de pacientesponderación por puntuación de propensiónPosttraumatic stress disorderprincipios FAIR para la recuperación de datospropensity score weightingrecoveryrecuperaciónsubstance use disorderTrastorno de estrés postraumáticotrastorno por uso de sustancias

Identifiers

PMID42804292
PMCPMC13637689

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.