Evidence map›Paper›PMID 42803988›Full record

ArticleResearch on child and adolescent psychopathology2026

Symptom Networks, Developmental Pathways, and Intervention Evidence for Co-occurring Anxiety and Depression in Children and Adolescents: A Scoping Review.

Rui Hu, Xuanyuan Chen

Abstract readScoping Review
In one paragraph

Article in Research on child and adolescent psychopathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rui HuSchool of Public Administration, Sichuan University, Chengdu, 610065, China.
Xuanyuan ChenSchool of Public Administration, Sichuan University, Chengdu, 610065, China. chenxuanyuan@scu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anxiety and depression frequently co-occur in children and adolescents, but studies of their joint presentation use different units of analysis. This scoping review examined how those approaches connect and where evidence remains limited. We searched PubMed, Web of Science Core Collection, Scopus, and APA PsycINFO for English-language studies available from 2010 to 11 May 2026. We mapped 205 eligible studies across eight non-exclusive empirical themes and interpreted their distribution from a developmental perspective. Study designs varied with the constructs examined. Among 52 symptom-network studies, 37 analysed cross-sectional data and 15 used longitudinal or trajectory cohort designs. Only 16 of 170 risk-factor studies also evaluated treatment outcomes. One symptom-network study linked network-derived findings to a neurobiological measure. Developmental and geographical coverage was uneven. Three studies were child-focused, and the United States and China accounted for 69.27% of the evidence. The descriptive Global South aggregate accounted for 5.85%. These patterns identify priorities for longitudinal within-person research, developmental stratification, and studies linking symptom models to biological measures and intervention mechanisms. Locally validated measures and research in underrepresented settings are needed to assess whether findings transfer across populations.

Indexed as

AnxietyAnxiety DisordersDepressionAdolescentChildComorbidityEvidence GapsHumansAdolescentAnxietyChildComorbidityDepressionScoping review

Identifiers

PMID42803988
PMCPMC13619781

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.