Evidence map›Paper›PMID 42803986›Full record

ArticleJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2026

Extracorporeal cardiopulmonary resuscitation for cardiogenic shock in a Jehovah's witness.

Derek K Afflu, Louis F Chai, Hiromu Kehara, Sean M Baskin, Yoshiya Toyoda, Roh Yanagida

Abstract readCase Reports
In one paragraph

Article in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Derek K AffluLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Louis F ChaiLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Hiromu KeharaLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Sean M BaskinLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Yoshiya ToyodaLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.
Roh YanagidaLewis Katz School of Medicine at Temple University, Philadelphia, PA, USA. ryanagida@att.net.ORCID http://orcid.org/0000-0002-4474-8075

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Veno-arterial (V-A) and veno-venous (V-V) extracorporeal membrane oxygenation (ECMO) are frequently employed in the management of cardiopulmonary failure in critically ill patients. Utilization, however, is controversial in the Jehovah's Witness (JW) population as temporary mechanical circulatory support (tMCS) typically is associated with blood loss requiring transfusions. Despite this fact, use of ECMO is still feasible in this population while avoiding blood transfusions and there have been few reported cases in the literature. However, its use as part of cardiopulmonary resuscitation is limited. Multiple strategies have been employed to limit blood loss and maximize endogenous hematopoiesis to assist in maintaining normal physiology while utilizing tMCS. Though these tactics are most useful when applied in the preintervention setting, they are applicable in the emergency setting including extracorporeal cardiopulmonary resuscitation (ECPR). This can be achieved with conscientious cannulation technique and circuit management. Presented here is a case report of the successful use of V-A ECMO in the resuscitation for a JW, avoiding blood product transfusions. The protocol utilized to eliminate the need for blood transfusions is also discussed. This approach adds to the growing body of evidence emphasizing that the use of tMCS as part of bloodless medicine practice is feasible, even in the emergency setting.

Indexed as

Cardiopulmonary ResuscitationExtracorporeal Membrane OxygenationJehovah's WitnessesShock, CardiogenicBlood TransfusionHumansBloodless medicineCardiopulmonary resuscitationExtracorporeal membrane oxygenationJehovah’s witnessMechanical circulatory support

Identifiers

PMID42803986
PMCPMC13619714

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.