Evidence map›Paper›PMID 42803937›Full record

ArticleEuropean radiology2026

5.0 T versus 1.5 T and 3.0 T upper abdominal MRI: a prospective two‑cohort study of image quality and diagnostic confidence.

Liuhong Zhu, Danlan Lian, Funan Wang, Anjie Xie, Jiaqi Wang, Hao Liu, Jianjun Zhou

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Article in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Liuhong Zhu *Department of Radiology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China.
Danlan Lian *Department of Radiology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China.
Funan WangDepartment of Radiology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China.
Anjie XieDepartment of Radiology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China.
Jiaqi WangCollaborative Innovation Department, United Imaging Healthcare, Shanghai, China.
Hao LiuDepartment of Radiology, Zhongshan Hospital, Fudan University, Shanghai, China. liuhaozsxm@163.com.ORCID http://orcid.org/0000-0001-8867-5122
Jianjun ZhouDepartment of Radiology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, China. zhoujianjunzs1@126.com.

Funding

The Medical Innovation Project from the Fujian Provincial Health and Wellness Science and Technology Program 2024CXB020
6 · The paper itself

Abstract

objectivesTo compare 5.0 T magnetic resonance imaging (MRI) image quality versus 1.5 T and 3.0 T in patients and healthy volunteers, so as to validate its clinical feasibility. MATERIALS AND

methodsThis prospective study included a patient cohort (348 consecutive patients undergoing upper abdominal MRI) and a healthy volunteer cohort (31 volunteers scanned on all three scanners). Two radiologists independently assessed image quality subjectively (5-point Likert scale: anatomical detail, artifacts, overall image quality, diagnostic confidence) and measured signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR). Subjective and objective metrics were compared across field strengths using overall and pairwise comparisons.

resultsObjective metrics (left/right/mean liver SNR, muscle/spleen SNR, liver-spleen CNR) showed a significant gradient of 5.0 T > 3.0 T > 1.5 T in both cohorts (all p < 0.001). Subjectively, compared with 1.5 T and 3.0 T, 5.0 T received the lowest scores for cardiac motion artifact and liver signal uniformity on T2-weighted imaging (T2WI) and showed greater distortion and ghosting artifacts on diffusion-weighted imaging (DWI) (all p < 0.05). Nevertheless, 5.0 T was significantly superior in anatomical detail, SNR, and overall image quality (all p < 0.05). In patients, 5.0 T also achieved the highest diagnostic confidence (p < 0.05). Results from healthy volunteers were largely consistent with those from the patient cohort.

conclusion5.0 T upper abdominal MRI, with a primary focus on liver imaging, is clinically feasible, offering superior anatomical detail, SNR, overall image quality, and diagnostic confidence over 1.5 T and 3.0 T, though cardiac motion artifacts, liver signal inhomogeneity on T2WI, and geometric distortion on DWI require further optimization. KEY POINTS: Question Is 5.0-T MRI superior to 1.5 T and 3.0 T for liver imaging, and does its diagnostic benefit differ between diseased and non-diseased livers? Findings 5.0 T provided significantly higher SNR, image quality, and diagnostic confidence than 1.5 T and 3.0 T, despite increased cardiac motion and liver signal inhomogeneity. Clinical relevance 5.0-T MRI significantly improves liver image quality and diagnostic confidence over 3.0 T and 1.5 T, supporting its clinical utility despite increased artifacts that require further optimization.

Indexed as

5.0 TArtifactsImage qualityUltra-high-field MRIUpper abdomen

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.