Evidence map›Paper›PMID 42803879›Full record

ReviewBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2026

Bacilli the most important biocontrol agent in Brazilian agriculture: from mechanisms of action to market adoption.

Wagner Bettiol, Roberto Lanna-Filho, Cristiano Limberger

Abstract readReview
In one paragraph

Review in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wagner BettiolEmbrapa Meio Ambiente, Rod. SP-340 Km 127,5, Jaguariúna, SP, 13.918-110, Brazil. wagner.bettiol@embrapa.br.ORCID http://orcid.org/0000-0001-7724-6445
Roberto Lanna-FilhoDepartamento de Fitossanidade, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, 91540-000, Brazil.
Cristiano LimbergerKynothec Brasil, R. Dr. Eraldo Aurélio Franzese, 184, Valinhos, SP, 13271-608, Brazil.

Funding

CNPQ 305557/2023-8
6 · The paper itself

Abstract

Bacilli have become one of the most commercially significant groups of microorganisms used in agricultural biocontrol products in Brazil. Their ability to form endospores and produce a wide range of metabolites allows them to control plant diseases, promote plant growth, and alleviate stress, supporting their extensive adoption in crop protection systems. This study analyzes the Brazilian market for Bacillus-based products used in plant disease management and summarizes their mechanisms of action. Data on commercial registrations, active strains, product formulations, and target diseases were compiled from Brazilian national regulatory databases. Market indicators, such as potential area treated (PAT) and turnover, were estimated using structured agricultural surveys conducted across Brazil during the 2019/2020 and 2024/2025 crop seasons, the latter encompassing more than 16,000 interviews with farmers and agricultural managers. By December/2025, 297 Bacillus-based products containing 126 strains were commercialized in Brazil, with Bacillus amyloliquefaciens, B. subtilis, B. velezensis, and B. pumilus being the most prominent species. These products are applied via seed treatment, soil drenching, furrow, and foliar spraying to manage fungal, bacterial, and nematode diseases. During the analyzed period, PAT increased from 7.5 to 37.2 million hectares (391% growth) and turnover increased from US$114.31 to US$403.17 million (252% growth). Currently, Bacillus-based products accounted for approximately 48% of the Brazilian biological control market, highlighting the prevalence of this genus in the sector. Overall, these results demonstrate how advances in microbial biotechnology, regulatory development, and farmer adoption have positioned Bacillus spp. as key components of the rapidly expanding biocontrol industry.

Indexed as

AgricultureBacillusBiological Control AgentsPest Control, BiologicalPlant DiseasesBrazilCrops, AgriculturalBiological Control AgentsBacillus-based productsBiological controlBrazilian biocontrol market

Identifiers

PMID42803879
PMCPMC13620009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.