Evidence map›Paper›PMID 42803757›Full record

ArticleTransboundary and emerging diseases2026

Seroprevalence of Epizootic Hemorrhagic Disease Virus in Cattle, Sheep, and Goats in New York State From 2022 Through 2025.

Elisha Frye, Patrick Connelly, Krysten Schuler, Jennifer Powers, Melissa Aprea, Diego G Diel

Abstract read
In one paragraph

Article in Transboundary and emerging diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elisha FryeDepartment of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca 14853, New York, USA, cornell.edu.ORCID https://orcid.org/0000-0002-7784-6771
Patrick ConnellyLouis Calder Center Biological Field Station, Fordham University, 31 Whippoorwill Rd, Armonk 10504, New York, USA, fordham.edu.
Krysten SchulerAnimal Health Diagnostic Center, College of Veterinary Medicine, Cornell University, 240 Farrier Road, Ithaca 14853, New York, USA, cornell.edu.ORCID https://orcid.org/0000-0002-0515-3589
Jennifer PowersAnimal Health Diagnostic Center, College of Veterinary Medicine, Cornell University, 240 Farrier Road, Ithaca 14853, New York, USA, cornell.edu.
Melissa ApreaAnimal Health Diagnostic Center, College of Veterinary Medicine, Cornell University, 240 Farrier Road, Ithaca 14853, New York, USA, cornell.edu.ORCID https://orcid.org/0000-0002-5833-1940
Diego G DielDepartment of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca 14853, New York, USA, cornell.edu.ORCID https://orcid.org/0000-0003-3237-8940

Funding

Federal Capacity Funds 7003411National Institute of Food and AgricultureU.S. Department of Agriculture
6 · The paper itself

Abstract

Epizootic hemorrhagic disease (EHD) virus (EHDV) is a vector-borne virus transmitted by Culicoides midges that infects domestic and wild ruminants. EHDV causes high mortality in white-tailed deer (WTD) and oral lesions mimicking foot and mouth disease (FMD) in cattle. Small ruminants (e.g., domestic sheep, domestic goats) seroconvert but do not typically develop disease. In 2021, ~2100 WTD deaths were attributed to EHD in New York (NY) State. That same year, an EHD outbreak at a NY dairy resulted in a foreign animal disease (FAD) investigation to rule out FMD, and EHDV was detected in a captive bison herd in NY. In response to the EHD outbreak affecting wildlife, agricultural, and exhibition animals, serum samples from cattle, sheep, and goats submitted to the Cornell University College of Veterinary Medicine Animal Health Diagnostic Center (AHDC) were tested for EHDV antibodies. The samples tested in our surveillance study included samples collected during and after Culicoides vector activity (July-January) over three seasons from 2022 to 2025. A total of 5698 samples comprising 4874 cattle and 824 small ruminants were tested using the agar gel immunodiffusion assay (AGID). Season 1 had 0.6% seroprevalence (10/1719), season 2 had 0.7% seroprevalence (15/2021), season 3 had 0.5% seroprevalence (9/1958) with an overall seroprevalence of 0.6%. Neutralizing antibody (NA) titers were determined on all AGID positive samples for EHDV serotypes 1, 2, and 6. There were 20 samples positive for EHDV serotype 2 (NA titers from 1:40 to ≥ 1:1280); 11 samples positive for EHDV serotype 6 (NA titers from 1:10 to 1:640); and three animals with cross-reaction amongst serotypes. Of the 34 positive samples, 31 were from cattle and 3 were from sheep. Nineteen samples were from counties with large numbers of WTD deaths attributed to EHDV in 2021 or counties with cases of EHDV in cattle. This data indicates that EHDV serotypes 2 and 6 subclinically infected a small number of domestic ruminants in NY from 2022 to 2025.

Indexed as

Cattle DiseasesGoat DiseasesHemorrhagic Disease Virus, EpizooticReoviridae InfectionsSheep DiseasesAnimalsAntibodies, ViralCattleGoatsNew YorkSeroepidemiologic StudiesSheepAntibodies, Viralantibodiescattleepizootic hemorrhagic diseasegoatNew York Stateseroprevalencesheepwhite-tailed deer

Identifiers

PMID42803757
PMCPMC13618552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.