ReviewActa dermato-venereologica2026
Summary of Best Evidence for Wound Management in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.
Review in Acta dermato-venereologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but life-threate-ning mucocutaneous reactions characterized by extensive epidermal detachment and systemic complications. Wound management is central to survival and long-term outcomes, yet standardiz-ed care pathways remain controversial and in-consistently implemented. This study aimed to systematically synthesize the best available evidence on wound management for patients with SJS/TEN to support clinical decision-making and optimize clinical outcomes. A comprehensive search of major international and Chinese databases and authoritative websites was conducted from January 2010 to May 2025 to collect relevant clinical decisions, guidelines, expert consensus, systematic reviews, and evidence summaries. Two reviewers independently screened and evaluated the literature, and then extracted and summarized evidence using the JBI grading system. A total of 14 high-quality publications met the inclusion criteria, yielding 28 pieces of best evidence across seven7 domains: wound assessment, conservative management, surgical approach, dressing selection, pain management, infection prevention and surveillance, and hospital setting. Among them, 11 recommendations were graded as strong and 17 as weak. This evidence-based synthesis provides practical guidance for wound management in SJS/TEN and supports the development of standardized care protocols to promote epithelial recovery, reduce complications, and improve quality of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.