Evidence map›Paper›PMID 42803610›Full record

ReviewJournal of veterinary internal medicine2026

Current knowledge of intermittent photic stimulation for electroencephalography in dogs.

Robert John Shwarzman, Marnie Ford, Alex M K Chan, Luis Gaitero, Fiona M K James

Abstract readReview
In one paragraph

Review in Journal of veterinary internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robert John ShwarzmanDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Canada.ORCID 0009-0001-7612-1322
Marnie FordDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Canada.ORCID 0009-0002-9640-8045
Alex M K ChanDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Canada.ORCID 0000-0003-2736-6451
Luis GaiteroDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Canada.ORCID 0000-0001-8101-5594
Fiona M K JamesDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Canada.ORCID 0000-0003-4331-4993

Funding

Natural Sciences and Engineering Research Council of Canada RGPIN-02606-2021
6 · The paper itself

Abstract

Intermittent photic stimulation is a standardized activation procedure for electroencephalography in humans that increases the detection of epileptic activity and improves diagnostic yield. However, its application in veterinary medicine remains inconsistent and methodologically heterogeneous. This narrative review synthesizes current knowledge regarding intermittent photic stimulation in dogs, critically evaluates variability in stimulus design, vigilance state, and electrode montage, and proposes a framework to support standardization in veterinary practice. Published veterinary studies demonstrate that photic stimulation can provoke generalized spike-wave and polyspike-wave discharges in selected epilepsy syndromes of dogs, particularly during awake recordings. However, protocols vary substantially in frequency range, light intensity, eye state control, flash duration, vigilance state, and lamp distance. Sedation and general anesthesia appear to attenuate retinal and thalamocortical responsiveness, decreasing the likelihood of eliciting photoparoxysmal responses. In addition, sparse and inconsistent electrode arrays limit spatial interpretation of photic responses and hinder cross-study comparisons. Drawing on established methodology used in humans and emerging veterinary data, this review outlines practical recommendations for standardized awake testing, defined stimulus parameters, and improved spatial sampling. Harmonized protocols may enhance diagnostic sensitivity, facilitate identification of photosensitive epilepsy syndromes in dogs, and strengthen translational alignment between epileptology in humans and animals. Standardization of intermittent photic stimulation represents an opportunity to improve the clinical utility and reproducibility of electroencephalography in dogs.

Indexed as

Dog DiseasesElectroencephalographyEpilepsyPhotic StimulationAnimalsDogsepilepsyepilepsy syndromesphotoparoxysmal responsephotosensitivitysedationstandardizationtranslational neurology

Identifiers

PMID42803610
PMCPMC13617574

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.