ReviewOncogene2026
Metabolites and cancer metastasis.
Review in Oncogene, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Over the past decades, metastasis research has largely emphasized genetic and epigenetic regulators. Emerging evidence indicates that metabolites-including sugars (glucose, fructose), antioxidant vitamins, glutathione, lipids (palmitic acid, cholesterol), and amino acids (glutamine, aspartate, BCAAs)-can critically influence metastasis in a context-dependent manner by driving or restraining progression via metabolic reprogramming and signaling modulation. This review examines how cancer cells re-modulate core metabolic pathways to adapt and metastasize, summarizes how endogenous metabolites, dietary bioactive compounds, metabolic toxins, and pharmacological agents regulate metastasis, and discusses new concepts and perspectives on metabolic regulation of tumor metastasis, and outlines future directions in metabolite-driven tumor metastasis. The metabolic dependencies of metastasis provide a rational basis for intervention through integrated nutritional and therapeutic strategies.
Identifiers
42802236What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.