Evidence map›Paper›PMID 42802231›Full record

ArticlePflugers Archiv : European journal of physiology2026

Analysis of sodium self-inhibition of the epithelial sodium channel (ENaC) using classical and medium-throughput automated two-electrode voltage-clamp recordings.

Karen Lizet Luján López, Nadja Furtwängler, Carol Merlin Frank, Mike Althaus, Oliver Rauh

Abstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Karen Lizet Luján LópezInstitute for Functional Gene Analytics, Bonn-Rhein-Sieg University of Applied Sciences, Von-Liebig-Str. 20, Rheinbach, 53359, Germany.ORCID http://orcid.org/0009-0000-4486-4984
Nadja FurtwänglerInstitute for Functional Gene Analytics, Bonn-Rhein-Sieg University of Applied Sciences, Von-Liebig-Str. 20, Rheinbach, 53359, Germany.
Carol Merlin FrankInstitute for Functional Gene Analytics, Bonn-Rhein-Sieg University of Applied Sciences, Von-Liebig-Str. 20, Rheinbach, 53359, Germany.
Mike AlthausInstitute for Functional Gene Analytics, Bonn-Rhein-Sieg University of Applied Sciences, Von-Liebig-Str. 20, Rheinbach, 53359, Germany. mike.althaus@h-brs.de.ORCID http://orcid.org/0000-0002-3554-7538
Oliver RauhInstitute for Functional Gene Analytics, Bonn-Rhein-Sieg University of Applied Sciences, Von-Liebig-Str. 20, Rheinbach, 53359, Germany. oliver.rauh@h-brs.de.ORCID https://orcid.org/0000-0003-1082-8656

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epithelial sodium channel (ENaC) is a key regulator of electrolyte homeostasis and blood pressure. A characteristic ENaC feature is sodium self-inhibition (SSI), a rapid autoregulatory mechanism in which extracellular Na

Indexed as

Epithelial Sodium ChannelsPatch-Clamp TechniquesSodiumAnimalsHumansIon Channel GatingXenopus laevisEpithelial Sodium ChannelsSodiumAutomated electrophysiologyENaCEpithelial Sodium ChannelSodiumSodium self-inhibitionTwo-electrode voltage-clamp

Identifiers

PMID42802231
PMCPMC13616839

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.