Evidence map›Paper›PMID 42801787›Full record

Trial reportBehavioural neurology2026

Unilateral Exoskeleton Training for Balance/Gait in Hemiplegic Stroke: Pilot Study.

Shaoting Zhou, Sen Wang, Xueying Qu, Jing Fan, Hanlin Xu, Linyu Chen, Lingyu Liu

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Behavioural neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shaoting ZhouDepartment of Neurology and Neurological Rehabilitation, Shanghai Disabled Persons' Federation Key Laboratory of Intelligent Rehabilitation Assistive Devices and Technologies, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai, China, tongji.edu.cn.ORCID https://orcid.org/0000-0002-3120-9355
Sen WangDepartment of Orthopedic Rehabilitation, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai, China, tongji.edu.cn.ORCID https://orcid.org/0009-0003-7188-1538
Xueying QuDepartment of Neurology and Neurological Rehabilitation, Shanghai Disabled Persons' Federation Key Laboratory of Intelligent Rehabilitation Assistive Devices and Technologies, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai, China, tongji.edu.cn.ORCID https://orcid.org/0000-0003-1395-0681
Jing FanDepartment of Neurology and Neurological Rehabilitation, Shanghai Disabled Persons' Federation Key Laboratory of Intelligent Rehabilitation Assistive Devices and Technologies, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai, China, tongji.edu.cn.ORCID https://orcid.org/0000-0003-4604-401X
Hanlin XuDepartment of Neurology and Neurological Rehabilitation, Shanghai Disabled Persons' Federation Key Laboratory of Intelligent Rehabilitation Assistive Devices and Technologies, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai, China, tongji.edu.cn.ORCID https://orcid.org/0009-0003-4785-8741
Linyu ChenDepartment of Neurology and Neurological Rehabilitation, Shanghai Disabled Persons' Federation Key Laboratory of Intelligent Rehabilitation Assistive Devices and Technologies, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai, China, tongji.edu.cn.ORCID https://orcid.org/0000-0002-1937-3339
Lingyu LiuDepartment of Neurology and Neurological Rehabilitation, Shanghai Disabled Persons' Federation Key Laboratory of Intelligent Rehabilitation Assistive Devices and Technologies, Shanghai Yangzhi Rehabilitation Hospital (Shanghai Sunshine Rehabilitation Center), Tongji University School of Medicine, Shanghai, China, tongji.edu.cn.ORCID https://orcid.org/0000-0001-6863-3937

Funding

National clinical key specialty construction project of China Z155080000004Shanghai Municipal Health Commission SHKFJS002ASongjiang District Science and Technology Commission Project of Shanghai 2023SIKIGG105Sunshine Clinical Research Cultivation Project of Yangzhi Rehabilitation Hospital Affiliated to Tongji University 2024CRTS003
6 · The paper itself

Abstract

objectiveThe aim of this study is to evaluate the effects of a unilateral-lower limb exoskeleton rehabilitation training robot on balance and lower limb function after stroke.

methodsIn this pilot study, stroke patients with hemiplegic at Tongji University Yangzhi Rehabilitation Hospital (between October 2022 and December 2023) were randomly assigned to either the robot group or the control group. The primary measure was the Berg balance scale (BBS), whereas secondary measures included the 10-m walking time test, 6-min walk test, three-dimensional gait analysis, and pain levels using the Hospital Anxiety and Depression Scale (HADS) and visual analogue scale (VAS).

resultsAmong 36 post-stroke hemiplegia patients (25 males; 18 per group), the robot group significantly outperformed the traditional group. The robot group improved BBS scores (5.50 ± 2.09 vs. 3.11 ± 1.50, p < 0.001), 6-min walking distance (15.89 ± 8.64 m vs. 9.73 ± 5.83 m, p = 0.017), and 10-m walking time reduction (8.82 ± 3.22 s vs. 6.83 ± 1.81 s, p = 0.030). Gait parameters also showed greater gains: hip flexion (3.57°±2.30° vs. 1.72°±2.15°, p = 0.018), knee flexion (5.28°±4.89° vs. 2.63°±2.37°, p = 0.046), and ankle dorsiflexion (4.81°±5.57° vs. 1.09°±4.19°, p = 0.030). Depression scores improved more in the robot group (2.89 ± 1.75 vs. 1.61 ± 1.20, p = 0.015). No significant differences occurred in anxiety or pain VAS scores (p > 0.05).

conclusionIntegrating a unilateral-lower limb exoskeleton rehabilitation robot with traditional therapy significantly enhances lower limb recovery in stroke patients with hemiplegia. Future large-scale randomized controlled trials and follow-up evaluations are needed to validate the current findings.

Indexed as

Exoskeleton DeviceHemiplegiaPostural BalanceStrokeStroke RehabilitationAgedFemaleGaitHumansLower ExtremityMaleMiddle AgedPilot ProjectsRoboticsTreatment OutcomeWalkingrehabilitationstrokeunilateral-lower limb exoskeleton rehabilitation training robotwalking function

Identifiers

PMID42801787
PMCPMC13616487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.