Evidence map›Paper›PMID 42801711›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Magnetically Guided Macrophage Immunobots Coordinate Iron-Metabolic Cascades and Immunogenic Ferroptosis for Tumor Immunotherapy.

Xirui Zeng, Yingfei Zhang, Chong Wu, Qijia Duan, Mengqi Fan, Kuan Wang, Shirong Cai, Immihan Ceren Yasa

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xirui Zeng *Robotics and Autonomous Systems Thrust, Systems Hub, The Hong Kong University of Science and Technology (Guangzhou), Guangzhou, China.ORCID https://orcid.org/0009-0000-0394-8209
Yingfei Zhang *Bioscience and Biomedical Engineering Thrust, Systems Hub, The Hong Kong University of Science and Technology (Guangzhou), Guangzhou, China.ORCID https://orcid.org/0009-0003-6441-1407
Chong WuDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Qijia DuanRobotics and Autonomous Systems Thrust, Systems Hub, The Hong Kong University of Science and Technology (Guangzhou), Guangzhou, China.ORCID https://orcid.org/0009-0001-5895-3811
Mengqi FanBioscience and Biomedical Engineering Thrust, Systems Hub, The Hong Kong University of Science and Technology (Guangzhou), Guangzhou, China.
Kuan WangBioscience and Biomedical Engineering Thrust, Systems Hub, The Hong Kong University of Science and Technology (Guangzhou), Guangzhou, China.ORCID https://orcid.org/0009-0004-4879-0117
Shirong CaiDepartment of Gastrointestinal Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.ORCID https://orcid.org/0000-0001-8315-9989
Immihan Ceren YasaRobotics and Autonomous Systems Thrust, Systems Hub, The Hong Kong University of Science and Technology (Guangzhou), Guangzhou, China.ORCID https://orcid.org/0000-0002-5013-7246

Funding

Guangdong Provincial Project 2024QN11Z154Guangzhou-HKUST(GZ) Joint Funding Program 2025A03J3800National Natural Science Foundation of China W2433114
6 · The paper itself

Abstract

Adoptive cell therapy (ACT) remains challenging in solid tumors, where poor tumor infiltration, metabolic heterogeneity, and an immunosuppressive tumor microenvironment (TME) constrain therapeutic efficacy. Here, we developed magnetically and metabolically programmed macrophage-based immune microrobots (immunobots) for active solid tumor immunotherapy. The immunobots are constructed by loading bone marrow-derived macrophages (BMDMs) with lipopolysaccharide (LPS)-modified Janus L1

Indexed as

biohybrid microrobotscellular immunotherapyferroptosismagnetic actuationtargeted tumor therapy

Identifiers

PMID42801711
PMCPMC13616292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.