Evidence map›Paper›PMID 42801706›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2

Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hongfang Wang *Department of Human Anatomy, Hebei Medical University, Shijiazhuang, China.ORCID https://orcid.org/0000-0001-6585-5913
Ziyao Wang *Grade 2023, 5+3 Clinical Medicine, Hebei Medical University, Shijiazhuang, China.
Dongyue Zuo *Department of Human Anatomy, Hebei Medical University, Shijiazhuang, China.
Zhaowen SuDepartment of Human Anatomy, Hebei Medical University, Shijiazhuang, China.
Bowen SongGrade 2023, Clinical Medicine, Hebei Medical University, Shijiazhuang, China.
Jiamin GaoDepartment of Human Anatomy, Hebei Medical University, Shijiazhuang, China.
Yizhou ZhangDepartment of Human Anatomy, Hebei Medical University, Shijiazhuang, China.
Ruiting ZhaoDepartment of Human Anatomy, Hebei Medical University, Shijiazhuang, China.
Linjie SunDepartment of Human Anatomy, Hebei Medical University, Shijiazhuang, China.
Mengdi LiGrade 2023, Clinical Medicine, Clinical College of Hebei Medical University, Shijiazhuang, China.
Yirui FanGrade 2023, Clinical Medicine, Clinical College of Hebei Medical University, Shijiazhuang, China.
Dandan GengDepartment of Human Anatomy, Hebei Medical University, Shijiazhuang, China.ORCID https://orcid.org/0009-0007-2672-8867
Lei WangDepartment of Human Anatomy, Hebei Medical University, Shijiazhuang, China.ORCID https://orcid.org/0009-0008-1173-345X

Funding

Key Laboratory of Neural and Vascular Biology of the Ministry of Education NV20230003National Natural Science Foundation of China 32471199National Natural Science Foundation of China 82201731Natural Science Foundation of Hebei Province H2023206164Natural Science Foundation of Hebei Province H2023206258Natural Science Foundation of Hebei Province H2024206135Yanzhao Golden Platform Project of Hebei Province HJYB202511
6 · The paper itself

Abstract

Nrf2 dysfunction is implicated in learning and memory deficits, but the involvement of non-coding RNAs in Nrf2-dependent cognitive regulation remains largely unexplored. Here, by analyzing the expression profiles of lncRNAs and mRNAs in the hippocampus of wild-type (WT) and Nrf2 knockout (Nrf2

Indexed as

IGF1learning and memorylncRNA Gm26550Nrf2

Identifiers

PMID42801706
PMCPMC13616242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.