Evidence map›Paper›PMID 42801605›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Smartphone-Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release.

Alexander Bruckmann, Adam Brooks Goodman, Myddelton C Parker, Mark Garren, Ji Eun Park, Chad Schmiedt, Hitesh Handa, Elizabeth J Brisbois

Abstract read
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In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexander Bruckmann *School of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia, USA.ORCID https://orcid.org/0009-0002-9611-7395
Adam Brooks Goodman *School of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia, USA.ORCID https://orcid.org/0009-0001-7594-8387
Myddelton C ParkerSchool of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia, USA.ORCID https://orcid.org/0009-0005-5779-2074
Mark GarrenSchool of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia, USA.ORCID https://orcid.org/0000-0001-5194-6558
Ji Eun ParkDepartment of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.ORCID https://orcid.org/0009-0002-9599-1179
Chad SchmiedtDepartment of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.ORCID https://orcid.org/0000-0003-1561-0736
Hitesh HandaSchool of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia, USA.ORCID https://orcid.org/0000-0002-9369-7374
Elizabeth J BrisboisSchool of Chemical, Materials, and Biomedical Engineering, College of Engineering, University of Georgia, Athens, Georgia, USA.ORCID https://orcid.org/0000-0002-9283-5448

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Institutional Career Development CoreKL2TR002381 · NCATS · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Anandi Nayan Sheth · 2017 to 2026
$14.1M
Prevention of catheter related infections via photoactive nitric oxide delivery deviceR01HL170574 · NHLBI · UNIVERSITY OF GEORGIA · PI Elizabeth Joy Brisbois · 2023 to 2026
$1.8M
NCATS NIH HHS KL2 TR002381NCATS NIH HHS KL2TR002381NCATS NIH HHS UL1 TR002378NCATS NIH HHS UL1TR002378NHLBI NIH HHS R01 HL170574NHLBI NIH HHS R01HL170574NIH HHS
6 · The paper itself

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) remains a major contributor to antimicrobial-resistant infections worldwide. Antimicrobial blue light (aBL, ∼405-450 nm) generates intracellular reactive oxygen species through excitation of endogenous chromophores, while nitric oxide (NO) induces complementary nitrosative and oxidative damage. S-nitrosothiols (RSNOs) provide a platform for visible-light-triggered NO release. Here, a synergistic antimicrobial strategy combining aBL with RSNO coatings was developed to simultaneously generate reactive oxygen and nitrogen species and evaluated against bacterial and fungal pathogens. Four RSNO donors (S-nitroso-N-acetylpenicillamine (SNAP), S-nitrosoglutathione (GSNO), S-nitroso-1-adamantanethiol (SNAT), and S-nitrosotriphenylmethanethiol (Ph

Indexed as

antimicrobialantimicrobial blue lightcontrolled releasenitric oxide

Identifiers

PMID42801605
PMCPMC13616380

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.