Evidence map›Paper›PMID 42801379›Full record

ArticleBiomechanics and modeling in mechanobiology2026

Validation of an ovine lung parenchyma material model with pressures representing the breathing cycle for high-velocity impacts.

Patricia K Thomas, Eugene Ablordeppey, Grace K Liverett, Philip J Brown, F Scott Gayzik

Abstract readValidation Study
In one paragraph

Article in Biomechanics and modeling in mechanobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patricia K ThomasDepartment of Biomedical Engineering, Wake Forest School of Medicine, 575 N. Patterson Ave Suite 530, Winston-Salem, NC, 27101, USA.ORCID http://orcid.org/0000-0002-5158-9084
Eugene AblordeppeyDepartment of Biomedical Engineering, Wake Forest School of Medicine, 575 N. Patterson Ave Suite 530, Winston-Salem, NC, 27101, USA.ORCID http://orcid.org/0009-0009-1382-570X
Grace K LiverettDepartment of Biomedical Engineering, Wake Forest School of Medicine, 575 N. Patterson Ave Suite 530, Winston-Salem, NC, 27101, USA.ORCID http://orcid.org/0009-0007-6369-5398
Philip J BrownDepartment of Biomedical Engineering, Wake Forest School of Medicine, 575 N. Patterson Ave Suite 530, Winston-Salem, NC, 27101, USA.
F Scott GayzikDepartment of Biomedical Engineering, Wake Forest School of Medicine, 575 N. Patterson Ave Suite 530, Winston-Salem, NC, 27101, USA. Scott.Gayzik@wfusm.edu.ORCID http://orcid.org/0000-0002-7443-5424

Funding

DEVCOM Army Research Laboratory W911NF2120034
6 · The paper itself

Abstract

Lung injury risk from high-velocity blunt impacts is thought to depend on lung pressure. Risk is typically assessed with finite element models (FEMs), but models do not typically account for lung pressure, nor do they account for lung viscoelasticity. The objective of this study is to translate and then validate a set of lung material models that consider both tissue viscoelasticity and pressure in silico. This was completed using one set of quasi-static simulations for translation and one set of dynamic simulations for validation to compare to experimental forces, where CORA was utilized. Digital image correlation (DIC) data of strain and displacement magnitude from the quasi-static experiments were also used to ensure proper material model translation. Three simulations were run for each loading case, where the only difference was the lung material properties to account for pressure (0, 4, and 10 cmH

Indexed as

LungModels, BiologicalParenchymal TissuePressureRespirationAnimalsBiomechanical PhenomenaComputer SimulationElasticityFinite Element AnalysisReproducibility of ResultsSheepStress, MechanicalDigital image correlationFinite element modelingLung biomechanicsValidation

Identifiers

PMID42801379
PMCPMC13616860

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.