ArticleAlzheimer's & dementia (Amsterdam, Netherlands)
Severity and progression of visual impairment and risk of dementia.
Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionVisual impairment is associated with dementia risk, but the role of severity and longitudinal change remains unclear. We examined whether visual impairment severity and its progression were associated with incident dementia.
methodsThis territory-wide cohort study followed 15,576 community-dwelling older adults without dementia at baseline for 16 years. Incident dementia was ascertained using International Classification of Diseases, Tenth Revision diagnoses or Clinical Dementia Rating scores of 1 to 3. Visual acuity was measured using the Snellen chart. Cox models estimated hazard ratios, excluding dementia cases occurring within the first 6 years to minimize reverse causation and adjusting for demographic, comorbidity, and lifestyle factors.
resultsModerate to severe visual impairment and faster visual acuity decline were associated with increased dementia risk. Severe visual impairment was associated with dementia onset 2.1 years earlier than normal vision. DISCUSSION: These findings strengthen the evidence for visual impairment as a dementia risk factor, supporting incorporation of visual assessment into dementia risk stratification. Trial Registration: The Chinese Clinical Trial Registry: ChiCTR1900023536.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.